What is the type of inheritance? What is known of the genotype of the male in the above cross? What is known of the genotype of the female in the above cross? Provide map distances if possible.
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- What is the type of inheritance?
- What is known of the genotype of the male in the above cross?
- What is known of the genotype of the female in the above cross?
- Provide map distances if possible.
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- EC1. In drosophila the cw (curly wings) gene and eb (ebony body) genes are found on the same chromosome 20 map units apart. A cross was made between an ebony bodied parental strain and a curly winged parental strain and the F1’s were test crossed. a) What are the genotypes of the parental strains? b) What are the genotypes of the F1’s? c) What is the genotype of the tester strain? d) What progeny phenotypes and genotypes do you expect, and in what proportions? For phenotypes use the mutant phenotype for any that the flies have, and wild-type if they have none. EC2. Here is a tetrad produced by mating a H Y strain to an h y strain. a) What is the tetrad type? b) What has recombined with what? EC3. In corn, a dihybrid for the recessive genes a and b is test-crossed. The distribution of the phenotypes is as follows: A B 122A b 118a B 81a b 79 a) Do the genes appear to be sorting independently? Look at map units here. b) Test your hypothesis with a chi-squared test.11. In Drosophila, three autosomal genes have the following map 5 m.u. 10 m.u. b + When a+ b+ c+ abc females are crossed to a bclabc males, how many flies of the phenotype a+ b c+ is expected among 1000 progeny assuming interference of 60%? A) 1 B) 2 C) 5 D) 3 E) 102. Drosophila females heterozygous for three recessive x-linked markers y (yellow bodies), ct (cut wings), and m (miniature wings) were crossed to y ct m males and the following progeny were obtained. F1 Phenotype Yellow, cut, miniature Wildtype Yellow Cut, miniature miniature Number cut 60 63 20 13 Yellow, cut 15 Yellow, miniature 5 22 2 a) F1 Genotype b) Recombinant or Parental? c) SCO, DCO, or NONE? a) Fill in the table with the genotypes of each progeny type, use + to indicate wildtype/dominant traits, show separate homologues. b) In the table, identify whether each progeny type is Recombinant (R) or Parental (P). c) In the table, identify whether each progeny type results from a single crossover (SCO), a double crossover (DCO), or no crossing over (NONE). d) Diagram the parental cross, clearly indicating allelic contributions from each homologue of parental flies. Heterozygous wild-type Female Fly X Hemizygous mutant Male fly // // e) Draw the genetic map showing correct order and…
- Another gene in Drosophila determines wing length. The dominant wild-type allele of this gene produces long wings; a recessive allele produces vestigial (short) wings. A female that is true- breeding for red eyes and long wings is mated with a male that has purple eyes and vestigial wings. F1 females are then crossed with purple-eyed, vestigial-winged males. From this second cross, a total of 600 offspring are obtained with the following combinations of traits: 252 with red eyes and long wings 276 with purple eyes and vestigial wings 42 with red eyes and vestigial wings 30 with purple eyes and long wings Are the genes linked, unlinked, or sex-linked? If they are linked, how many map units separate them on the chromosome?4. In Drosophila melanogaster, a yellow-bodied (dark coloured) male with vestigial (underformed) wings is crossed to a wildtype female (brown body, red eyes). The F1 generation are all wildtypes. An F1 male and female are crossed and the F2 progeny consists of 16 vestigial-winged males with yellow bodies, 48 yellow males with normal wings, 15 males with vestigial wings and yellow bodies, 49 wildtype males, 31 vestigial winged females with brown bodies and 97 wildtype females. Explain the inheritance pattern of the 2 genes.4) You design Drosophila crosses to provide recombination data for gene (A), which is located somewhere on the chromosome shown below: Short aristae Long aristae (appendages on head) III Black body Gray body Mutant phenotypes Cinnabar eyes 48.5 57.5 Red eyes 67.0 Vestigial wings Normal wings Brown eyes 104.5 Red eyes Wild-type phenotypes Gene (A) has a recombination frequency of 14% with the vestigial-wing locus and 23% with the brown- eye locus. Where is gene (A) located on this chromosome?
- You are given a Drosophila female that looks wild-type but is heterozygous for mutations intan body (t), miniature wings (m), and white eyes (w). You test cross this female with a tanbodied, miniature winged, and white-eyed homozygous mutant male, and you obtain thefollowing 1400 progeny: Phenotype : number+ + + : 608t m w : 516+ m w : 2t + + : 6+ m + : 39t + w : 46+ + w : 81t m + : 102 Calculate the distance between each pair t-m, m-w, and t-w only using the number ofrecombinants between them (i.e. ignoring the gene in the middle). Draw a linear map with thedistances between genes.1. Please consider the following pedigree. I 1 2 II 1 a) Assume that colour is controlled by a single sex-influenced gene where orange is expressed preferentially in females. Individuals I-1 and I-2 are homozygous for orange and blue respectively. Which individual/s in generation II will be blue? b) If colour is a controlled by cytoplasmic DNA, which individual/s in generation II will be orange?1. Please consider the following pedigree. I 1 II 1 a) Assume that colour is controlled by a single sex-influenced gene where green is expressed preferentially in males. Individuals I-1 and I-2 are homozygous for red and green respectively. Which individual/s in generation II will be red? b) If colour is a controlled by cytoplasmic DNA, which individual/s in generation II will be green?
- 4. The diagram below shows the original order of the genes on an autosome in Drosophila: C D EFGHI In each of the chromosomes illustrated below, this original chromosome has undergone a different structural rearrangement. Name the specific type of structural rearrangement that has occurred and draw a diagram to show how each would synapse with the normal chromosome during meiosis. (A) C D EFEFGHIJ (B) C D EIHG FJ (C) C D E F3. Two Drosophila flies that had normal (transparent, long) wings were mated. In the progeny, two new phenotypes appeared, dusky wings (having a semi-opaque appearance) and clipped wings (with squared ends). The progeny were as follows: Females: Males: 179 transparent, long 58 transparent, clipped 92 transparent, long 89 dusky, long 28 transparent, clipped 31 dusky, clipped a) Provide a genetic explanation for these results, showing genotypes of parents and of all progeny classes under your model. b) Design a test for your model.166. In Drosophila crossing over occurs in female but not in male. Gene A and B are 10 map unit apart on chromosome. A female Drosophila with genotype AB/ab and male Drosophila with genotype AB/ab. How many type of gametes are produced by female and male Drosophila respectively (1) 4 types : 2 types (2) 2 types : 2 types (3) 4 types : 4 types (4) 4 types : one types