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what are the complications or the low-reliability in determining the value of KM using graphical methods from a Michaelis-Menten Plot

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter3: Transmission Of Genes From Generation To Generation

Section3.7: Mendelian Inheritance In Humans

Problem 2EG: For most cases, a p value of 0.05 is used to determine whether results fit expected values. Is this...

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Please discuss the value of international normalized ratio (INR) as a test. Why do you think this is more reliable that the ordinary PT.
Answer briefly: Discuss the value of international normalized ratio (INR) as a test. Why do you think this is more reliable that the ordinary PT.
Graphically derive the value of KM from a Michaelis-Menten Plot
The graph of the Michaelis-menten equation, vo against [So] is unsatisfactory as a means of determining Vmax and Km. Briefly discuss why this is the case. How did lineweaver and buck overcome this problem?
For most cases, a p value of 0.05 is used to determine whether results fit expected values. Is this a magic number, or could p values be set more stringently, say 0.01, or more lax, say 0.10? What effect would these values have on the reliability of the chi-square test?
What value of [S], as a fraction of KM, is required to obtain 80% of Vmax? (Hint: use the MM equation, and algebra.) Express your answer as the fraction/multiple of KM needed, for example, if your answer is 2.75 times KM, then enter "2.75" or if your answer is 1/2 times KM, then enter "1/2" or "5" Don't include "x" or "times" just the number.
Briefly explain why the Tm measured in the experiment is different from the Tm predicted from Marmur and Doty equation. please provide the references.
How would you calculate the expected values from the observed in order to use the chi-squared test?
write the solution using the Hardy-Weinberg computation
Write Cif only statement A is correct, Hif only statement B is correct, Eif both statements are correct, Mif both statements are incorrect. A. For the Lineweaver-Burk plot, the slope of the line reflects the ratio between the maximum velocity and the Michaelis constant. B. Meanwhile, the y-intercept is the maximum velocity.
Give only typing answer with explanation and conclusion Assuming the requirements are met for the BLEU score study, what is the margin of error for a 95% confidence interval for the true mean BLEU score?
Can you explain how to find the answer and the calculation?