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Warm autoimmune hemolytic anemia, WAIHA, frequently have antibody specificity of:
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- In a blood transfusion, if the donor and recipient blood types are not matched correctly, it may result in a: a) Type I hypersensitivity reaction O b) Type II hypersensitivity reaction c) Type III hypersensitivity reaction d) Type IV hypersensitivity reactionThe figure above depicts an antibody. For the labeled areas, which statement among A-D is not correct? A) O Mature, functional IgA antibodies possess a total of two sites labeled A B) O Your IgM antibodies are all similar in these areas: A C) O During opsonization, area B would bind to a bacterium D) O Your IgD antibodies are all different in this area: B 111 E) O None are matched correctly. B.Describe the following antigen antibody reactions in serology: Mechanism Function in serology Example of method a) Precipitation b) Agglutination c) Neutralizing d) Complement fixation
- Which is not a direct consequence of an antibody antigen interaction? A) O clump or agglutinate antigens B) O neutralization of toxin C) O prevent adherence of pathogens D) O stimulation of B cells E) O all the above are consequences of an antibody antigen interactionAutoimmunity produces reactions that resemble which of the following hypersensitivity reactions? a)Type I, II, III and IV b)Type II, III and IV c)Type I, II and III d)Type I, III an IV e)none of the choices are correct. A) What is the significance of producing monoclonal antibodies? B) What is the role of cell culture in production of monoclonal antibodies? C) Name and briefly explain the use of any 4 commercially available monoclonal antibodies.
- For the following questions, specify which immunoglobulin is being described, according to the following key: a) IgA b) IgE c) IgG d) IgM e) more than one 33) Produced early in infection with high avidity 34) Labeled "secretory* 35) Most associated with parasitic infection 36) Generally produced most prominently following clearance of initial infection 37) Pentameric 38) Capable of forming a hybridoma 39) Associated with mast cell activation 40) Found predominantly in mucus secretionsSelect all of the following that are functions performed by different antibodies. a) Group of answer choices b) Attracting natural killer cells to destroy an infected cell. c) Blocking the ability of a pathogen to bind to a host cell d) Lysing a pathogen cell wall or lipid bilayer. e) Marking a pathogen so that innate immune cells destroy the pathogen. f) Helping complement proteins bind to a pathogen.1.The passing of antibodies into newborn babies by their mothers is known as: A) active immunity B) passive immunity C) primary immune response D) antigens The immune system responds to the antigens found on invading microorganisms by: A) producing antibodies B) antibodies preventing the microbe from causing infection C) marking the microbe so that it can be attacked by white blood cells D) all the above
- .A table comparing the biological characteristics of the five classes of immunoglobulins is shown below. Answer yes or no in the spaces provided, (You can draw the table in your answer paper) IgE IgD Biological activity a) Activates classical complement pathway b) Present on the membrane of the mature B cells c) Present in secretions d) Induces mast-cell degranulation e) Crosses placenta IgG IgA IgMWhat is the first step in the antigen-antibody interaction? A.) opsonization B.) epitope production C.) neutralization D.) phagocytosis E.) agglutination41) For the successful development of a vaccine to be used against a pathogen, it is necessary that A) the surface antigens of the pathogen do not change. B) a rearrangement of the B cell receptor antibodies takes place. C) all of the surface antigens on the pathogen be identified. D) the pathogen has only one epitope. E) the MHC molecules are heterozygous. 42) In the human disease known as lupus, there is an immune reaction against a patient's own DNA from broken or dying cells, which categorizes lupus as A) an allergy. B) an immunodeficiency. C) an autoimmune disease. D) an antigenic variation. E) a cancer.