The locations of numerous lacI- and lacIS mutations have been determined within the DNA sequence of the lacI gene. Among these, lacI- mutations were found to occur in the 5=-upstream region of the gene, while lacIS mutations were found to occur farther downstream in the gene. Are the locations of the two types of mutations within the gene consistent with what is known about the function of the repressor that is the product of the lacI gene?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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The locations of numerous lacI- and lacIS mutations have been
determined within the DNA sequence of the lacI gene. Among
these, lacI- mutations were found to occur in the 5=-upstream
region of the gene, while lacIS mutations were found to occur farther
downstream in the gene. Are the locations of the two types of
mutations within the gene consistent with what is known about
the function of the repressor that is the product of the lacI gene?

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