The local anaesthetic lidocaine is required by the British Pharmacopoeia to contain not less than99.0% and not more than 101.0% of C14H22N2O, calculated with reference to the anhydroussubstance.0.2093 g of a lidocaine sample was dissolved in anhydrous acetic acid and titrated with 0.1025 Mperchloric acid. 8.53 mL was required. Another sample of the lidocaine from the same batch wasfound to contain 0.78% water. Does the sample meet the BP requirements?

Fundamentals Of Analytical Chemistry
9th Edition
ISBN:9781285640686
Author:Skoog
Publisher:Skoog
Chapter13: Titrations In Analytical Chemistry
Section: Chapter Questions
Problem 13.5QAP
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The local anaesthetic lidocaine is required by the British Pharmacopoeia to contain not less than
99.0% and not more than 101.0% of C14H22N2O, calculated with reference to the anhydrous
substance.
0.2093 g of a lidocaine sample was dissolved in anhydrous acetic acid and titrated with 0.1025 M
perchloric acid. 8.53 mL was required. Another sample of the lidocaine from the same batch was
found to contain 0.78% water. Does the sample meet the BP requirements?

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