Сно сно CH,OH Fo но H- HO- H- Phosphorogluco- isomerase Phosphofructo- kinase Нехоkinase но H- но -OH АТР - ADP H- -он H. OH он H- -он H- -он Via H. OH OH АТР ADP CH,OH CH,OPO, CH,OPO,2 но- Glucose A CH,OPO,2 Fo CH;OPO, Fo CH,OH Fructose но H- biphosphate D HO- HPO, / NAD+/ Glyceraldehyde 3- phosphate dehydrogenase aldolase Triose VT phosphate isomerase сно н он E CH,OPO, HO- CH,OPO, O OPO, Via с он CH,OPO, H- он -он CH,OPO, G F OPO, of OH H3C OH Руruvic Acid
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- What biochemical reaction is catalyzed by γ-secretase? Why was it proposed that a chemical inhibitor of this activity might be a useful drug for treating Alzheimer’s disease? What possible side effects of such a drug would complicate this use?Choices for each phrases: a, b, y, t, v, e; gtp, cgt, atp, adp, camp, catp; gtp, gdp, atp, adp, camp, catp; histamine kinase, gaunylyl cyclamen, phosphorylation, adenylyl cyclaseWhat are four benefits of anaerobic glycolysis in tumor cells? https://www.nature.com/articles/s41598-019-40617-3#Tab1
- How does compromised pyruvate kinase activity lead to anemia?Met – Asn – Cys – Phe – Glu – Met – Leu – Arg – Ile – Asp – Glu – Gly – Leu – Arg – Leu – Lys – Ile – Tyr – Lys – Asp mRNA sequence (5’-3’)AUG – AAC – UGU – UUU – GAA – AUG – CUU – CGU – AUU – GAU – GAA – GGU – CUU – CGU – CUU – AAA – AUU – UAU – AAA – GAU - Write the dsDNA that encodes for this peptideThe Gq-protein and phospholipase C pathway are responsible for stimulating gluconeogenesis and glycogenolysis. What effect would an agonist or an antagonist have on gluconeogenesis and glycogenolysis?