signal of the ligand diminishes. The membrane-embedded enzyme uses GTP as a secondary messenger to initiate gene expression. The ligand attaches to both the GPCR and the membrane-embedded enzyme to activate the GPCR pathway. The ligand-bound GPCR sends a GTP molecule to an enzyme in the membrane and switches it into an active state.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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The G protein coupled receptor (GPCR) pathway elicits diverse intracellular responses in different cells. The basic steps of GPCR signaling are outlined in this diagram.

 

Which of the following statements correctly describes the process of GPCR signaling?

The GPCR activation is reversible after the signal of the ligand diminishes.
The membrane-embedded enzyme uses GTP as a secondary messenger to initiate gene expression.
The ligand attaches to both the GPCR and the membrane-embedded enzyme to activate the GPCR pathway.
The ligand-bound GPCR sends a GTP molecule to an enzyme in the membrane and switches it into an active state.
Ligand
Membrane-embedded
GPCR
enzyme
Signaling
intermediate
Intracellular
effector
Cellular
effects
Transcribed Image Text:Ligand Membrane-embedded GPCR enzyme Signaling intermediate Intracellular effector Cellular effects
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