Select all statements that are correct. Note there might be more than 1 correct statement.
Q: The atmospheric ratio of peroxyacetic nitric anhydride (PAN) to PAN + inorganic nitrite varies from…
A: The observation that high values of the PAN/PAN+inorganic nitrite ratio are associated with…
Q: Draw the resonance structure of a tripeptide peptide backbone, indicating the N- and C-terminal and…
A: Peptides are molecules composed of amino acids joined together through peptide bonds. The peptide…
Q: Match the following sugars with their corresponding descriptions. A Esculin Arabinose aldonitol G.…
A: Sugars are 'sweet-tasting' carbohydrates. Depending on their type, they can be either (a)…
Q: A tetrameric protein dissociates into dimers when the detergent sodium dodecyl sulfate (SDS) is…
A: Proteins are polymers of amino acids linked by peptide bonds. Proteins can be single chain or more…
Q: Please explain the difference between the oxygen dissociation curve created by myoglobin…
A: Blood is essential in the transport of oxygen throughout the body. Oxygen is carried in the blood by…
Q: Comparing chymotrypsin and subtilisin active site geometries on the assumption that their…
A: The approach of comparing the active site geometries of chymotrypsin and subtilisin to gain insights…
Q: Describe the amino acid illustrated above (at pH = 7.0). A. it is a polar, negatively-charged amino…
A: Every amino acid consists of a amino group and a carboxylic group, and a side chain R group. Amino…
Q: The catalytic mechanism of an enzyme found in the mitochondrial matrix (pH = 7.8) depends on an…
A: Dissociation of a weak acid is mathematically described by the Henderson-Hasselbalch equation: pH =…
Q: A segment of a protein-encoding gene sequence is given below. 5’-AAGTTTGGCACT-3’…
A: Transcription is the process by which the genetic information encoded in DNA is copied into a…
Q: Glyceraldehyde 3-phosphate + P₁ + NAD+ →→→ 1,3-bisphosphoglycerate + NADH + H+…
A: The payoff phase consists of 5 reactions that involves the conversion of Glyceraldehyde 3 Phosphate…
Q: The Neanderthal nuclear genome: A. Shows that Neanderthals inherited their ability to flake stone…
A: Homo neanderthalensis, or Neanderthal man, is an extinct human species that inhabited Europe and…
Q: ATP yield from glycolysis, TCA cycle and oxidative phospharylation (a) Compute the theoretical ATP…
A: Muscle cells can be cardiac muscle cells or skeletal muscle cells. The pair of electrons in NADH…
Q: What are the bond structures that help identify lipids? For example ester linkages and unsaturated…
A: Many biological processes rely on lipids, including energy storage, cell signalling, and membrane…
Q: 22. Explain why how the shape of an enzyme is related to the function. 23. How is the synthesis of…
A: Proteins have certain chemical characteristics, and enzymes are proteins. Tertiary or quaternary…
Q: 1. The Size of Cells and Their Components A typical eukaryotic cell has a cellular diameter of 50…
A: Electron microscope is an instrument to measure the ultrastructure of microscopic biological and…
Q: The unique cyclic structure of which of the following amino acids plays a central role in the…
A: c. Proline Proline is the only amino acid among the options with a cyclic structure that can…
Q: Are natural compounds such as cellulose and petroleum oil easier for microorganisms (eg. bacteria…
A: Microorganisms, such as bacteria, fungus, and algae, degrade and change organic compounds into…
Q: There are several sugars along with fructose and glucose that are isomeric, name them
A: The question asked for a list of sugars that are isomeric to fructose and glucose. Isomers are…
Q: Fatty acids can be gluconeogenic precursors in plants, but not animals. O True O False
A: Gluconeogenesis is a metabolic process that occurs in the liver and kidneys. It allows the body make…
Q: 4. Propose a two-step procedure to purify protein A from the other molecules (there are multiple…
A: Ion exchange chromatography is a powerful separation technique used to purify proteins and other…
Q: The pH of a solution is determined by concentration of salt ⓇB relative concentration of acids and…
A: The correct answer is B - relative concentration of acids and bases. pH is a measure of the acidity…
Q: Before we finish this part of the Activity, you’re going to begin summarizing what you’ve learned…
A: Functional Group: A functional group is a reactive portion of a molecule that is responsible for the…
Q: 1. Draw the structure of a cholesterol ester where cholesterol is esterified with palmitic acid. is…
A: The four classes of biological macromolecules are nucleic acids, proteins, lipids and carbohydrates.…
Q: For what chemical group is Millon's reagent a test? Write the formula and the name of the amino acid…
A: A biochemical test is a laboratory procedure for identifying or quantifying specific molecules or…
Q: In the traditional alkaline lysis method of Solution 1, what is the purpose of Tris pH 8 with HCl?
A: The traditional alkaline lysis method is a widely used and classic technique for isolating plasmid…
Q: Sweetzyme IT Extra is a trademarked immobilized enzyme formulation of glucose isomerase sold by the…
A: Vmax = k2[E0] =0.570 s-1 × 2.30×10-5 M = 1.311×10-5 M s-1
Q: Production of a recombinant protein by E. coli is proportional to cell growth. Ammonia is used as a…
A: Recombinant proteins are proteins that are produced through genetic engineering. They are created by…
Q: H₂C-O HC-O m F SMAAA H₂C-O m Saturated fat The diagram above is most specifically an example of a:…
A: Triglycerides or triacylglycerides or simple fat. are fatty acid esters of glycerols. In…
Q: Large globular proteins frequently are comprised of two or more recognizable structures that often…
A: The answer is b. domains. Large globular proteins are often composed of two or more distinct,…
Q: 6. A portion of a gene is shown below. 5'-ATGATTCGCCTCGGGGCTCCCCAGTCGCTGGTGCTGCTGACGCTGCTCGTCG-3'…
A: mRNA, or messenger RNA, is a type of RNA molecule that plays a central role in the process of…
Q: Describe the mechanism of action for the statins.
A: The mevalonate pathway is the metabolic pathway that produces cholesterol and other isoprenoids.…
Q: 6. A portion of a gene is shown below. 5'-ATGATTCGCCTCGGGGCTCCCCAGTCGCTGGTGCTGCTGACGCTGCTCGTCG-3'…
A: mRNA, or messenger RNA, is a type of RNA molecule that plays a central role in the process of…
Q: the strength of a ligand-protein binding is known as the binding sites a. conformation b.…
A: Protein ligand binding is a non-covalent binding between protein and ligand. This binding is…
Q: Optional) Describe the structure of DNA, discussing the DNA helix and the base pairs of ONA, the…
A: Introducion There are two types of nucleic acid present in our body. DNA and RNA. DNA acts as a…
Q: 4. On a TLC plate containing silica gel, which compound will have the largest R value when ethyl…
A: Rf value, also known as retention factor value, is a chromatographic measure that describes the…
Q: Given the amino acid chain below, get the (a) translation strand, (b) transcription strand strand,…
A: DNA is double stranded. There one strand is the template strand and the other is non-template. From…
Q: A 1/10 dilution of enzyme extract has been done for the protein assay. The experimental results are…
A: Here we are undertaking spectrophotometric analysis to find out the amount of protein in an unknown…
Q: Given the amino acid chain below, get the (a) translation strand, (b) transcription strand strand,…
A: Amino acids - are building blocks of proteins and alpha carbon of amino acids contains amine group,…
Q: Rapid regulation of pyruvate dehydrogenase complex is achieved via which of the following?…
A: Pyruvate is the end product of glycolysis. Under aerobic conditions, pyruvate is oxidised into…
Q: Fill in the chart below: Carbohydrate Protein Nucleic Acid Lipids HO H OH H H Circle one monomer in…
A: Carbohydrates, proteins , nucleic acids and lipids are the bio molecules. they are produced by…
Q: Microcytic anemia could be caused due to both iron deficiency anemia and thalassemia. could you…
A: Microcytic anaemia is a type of anaemia characterized by smaller-than-normal red blood cells. This…
Q: The four drugs A, B, C and D have the same IC50 values. Which of them has the highest efficacy? 100…
A: Drugs are substances that can alter the body and mind, and are often used illegally to create a…
Q: 7. Why is the doorway step needed to link glycolysis and the Krebs Cycle?
A: Glycolysis takes place inside the cytoplasm. Mitochondria is the site for kreb's cycle. Since both…
Q: what is the influent biodegradable chemical oxygen demand?
A: BOD stands for Biochemical Oxygen Demand. It is a measure of the amount of oxygen required by…
Q: 1. A substrate is converted to product using an enzyme that follows the mechanism below when an…
A: Since you have posted a question with multiple sub-parts, we willprovide the solution only to the…
Q: Table 1. Results of the Shrinkage Assay. Enter your assessment of the shrinkage of cell at the times…
A: A line graph represents the trend of the data on basis of differnt times. The y-axis usually shows…
Q: Lipids affect your health? why or why not
A: Lipids include fats, oils, waxes, and certain types of steroids. They are an essential component of…
Q: Please can you answer these questions regarding the “Evaluation of the thiol content of a selection…
A: Evaluating the thiol content of a selection of proteins involves measuring the concentration of…
Q: The typical human adult uses about 160 g of glucose per day. Of this, the brain alone uses 120 g.…
A: Fatty acids from triacylglycerols also should include in answer. After the glucose reserve has been…
Q: 1. Draw the peptide HSK below at pH 7 and give its overall charge at pH 2, 7, and 12:
A: The proteins are composed of twenty naturally occurring amino acids. The amino acids can be…
Step by step
Solved in 2 steps
- Select all statements that are correct. Enzyme inhibitors more than 1 correct statement. reduce the activation energy of a reaction 1 prevent the formation of the enzyme-substrate complex and no product can be formed reduce the rate at which products are formed by making it harder for the enzyme-substrate complex or the product to be formed prevent the product from being released from the enzyme reduce the activity of the enzyme Note there mightA medicinal chemist is trying to determine the mechanism of action of inhibitors she has synthesized. The relative change in KM and Vmax upon incubation of the targeted enzyme with each inhibitor is shown in the table below. Inhibitor A Inhibitor B Inhibitor C Using this data, the mechanism of action of Inhibitor C is: Uncompetitive TS‡ analog Mixed Inhibition Competitive Кмарр- Км 0 Non-competitive app - Vmax <0 <0 0 VmaxIdentify the type of enzyme inhibition each of the following inhibitor characteristics is associated with: 1. An inhibitor that decreases enzyme activity by binding to a site on the enzyme other that the active site. 2. An inhibitor that inactivates enzymes by forming a strong covalent bond of the enzyme acitve site.
- The following statements refer to enzyme inhibition. Match the statement to the one of the following descriptors to which it is best associated. Descriptors: competitive inhibition; non-competitive inhibition; un-competitive; covalent inhibition. 9a. Inhibition is not reversed even after the inhibitor (1) is removed from solution by dialysis or drug metabolism/excretion. 9b. Inhibitor and substrate reversibly compete for occupancy of a common binding site 9c. The inhibitor binds reversibly only to the preformed E.S (enzyme-substrate) complex forming an inactive E.S.I. 9d. The inhibitor binds reversibly and independently of substrate to an allosteric site producing E.I or a ternary E.S.I complex which can't form product. 9f. The relative amount of inhibition decreases as [S] (the concentration of substrate) increases and S better competes for occupancy of the active site.Question 5 Select all statements that are correct. Competitive inhibitors bind to the allosteric site on the enzyme Uncompetitive inhibitors bind to the substrate binding site Competitive inhibitors bind to the substrate binding site Competitive inhibitors are usually of similar size and shape than the substrate of the enzyme Non-competitive inhibitors can bind to the free enzyme but not to the enzyme-substrate complexEnzyme inhibition (compare and contrast reversible and irreversible inhibitors)
- USSE EUSS reaction rate substrate concentration Blue line - Enzyme alone Red line - Enzyme + unknown compound The 4 graphs above represent the change in enzyme kinetics with the individual addition of different compounds that could be categorized as either: allosteric inhibitors, allosteric activators, competitive inhibitors, activators or non-competitive inhibitors. Review the graphs above. Each graph represents the activity of an enzyme and the enzyme + the addition of an unknown compound. By comparing the kinetics of the enzyme alone to the enzyme + unknown, determine what type of compound was added to each of the 4 different solutions to elicit the observed change.Name: Sincere Frias Date: (0/2/2od0 Period Ced th nzy ck. Enzyme Models & Factors Affecting Enzyme Action PART I – Lock and Key Model st In this part you will construct models of enzymes. Remove the last page and cut all shapes out. 2. The different shapes will represent both enzymes and substrates. 3. Match up as many of the pieces as you can. 1. Questions 1. The enzyme maltase combines the substrates h ydrolysis + Starch molecule to produce the disaccharide maltose. 2. The enzyme ATPase combines the substrates_molecule and to produce the ATP (Adenosine TriPhospate). Iriglyceride 3. The enzyme lipase works on the substrate called 4. The enzyme phosphatase works on the substrate called 5. What is the relationship between the substrate and the enzyme?Which statements are false? Initial velocities of enzyme reactions are best obtained in the absence of product because it simplifies analysis. Initial velocities refer to the velocity of the reaction right after it is initiated. The velocity of the reaction as a function of measuring time are curved just like an isothermal binding curve because of substrate binding to the enzyme. Initial velocities correspond to the pre-steady state condition for free enzyme. Initial velocities can sometimes be measured by spectroscopy such as UV/Vis spectroscopy when monitoring the production of NADH from NAD+. The velocity of the reaction will eventually go to zero. The reaction will reach equilibrium because of the presence of the enzyme. It is always better to use substrate rather than product to measure enzyme kinetics.
- 1/Vo 1/[S] with I without I with I with I 1/vo without I *-*- 1/vo without I 1/[S] 1/[S] 3. The above graphs are lineweaver-burk plots that demonstrate how inhibitors affect Michaelis Menten enzymes. For each graph identify the type of inhibition and explain how you determined that this enzyme is kinetically demonstrating this type of inhibition.A purely competitive inhibitor of an enzyme has which of the following kinetic effects? decrease in Km increase in Vmax decrease in Vmax increase in Km Question 60 The Michaelis-Menten constant (KM) has the following characteristics, EXCEPT: The dimension for KM is concentration, such as molarity It is equal to ½ of Vmax It is the substrate concentration necessary to reach ½ of VmaxT/F Both competitive and noncompetitive inhibitors bind reversibly to an enzyme (E), thereby inhibiting its activity. These two kinds of inhibitors share the same site on the enzyme.
