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- Rank the relative nucleophilicity of the indicated species in ethanol. Most nucleophilic Least nucleophilic CHBОН CHCOOН CHно CH;COо CH3SRank the reactivity of the compounds below toward nucleophilic acyl substitution by writing the compounds' letters in the proper blanks in the box below. `NH CI Br CH3 CH3 A В C E rank compounds for acyl substitution reactivity most least reactive reactiveThe ether, CH3OCH2CH3, can be prepared by two different nucleophilic substitution reactions, one using CH3O- as nucleophile and the other using CH3CH2O- as nucleophile. Draw both routes.
- 12) Use the curved arrow formalism to show the movement of electron pairs in the following reaction and label each reactant as a nucleophile or an electrophile. CHÍNH CHỊCH, + CO Học Nha CH₂CH₂CIDenote how many nucleophilic centers are present in the following molecular structure (in case of polar bonds show clearly on the structure the dipoles õ+ and d-). :o: сноZaitsev's Rule refers to: which alkene is favored in a product mixture O how resonance contributors stabilize cations/anions/radicals O the stereochemistry of reaction intermediates/transition states O the stability of carbocation intermediates
- Consider compounds A-EExplain why pentane-2,4-dione forms two different alkylation products (Aor B) when the number of equivalents of base is increased from one totwo.Draw all of the substitution and elimination products formed from thegiven alkyl halide with each reagent: (a) CH3OH; (b) KOH. Indicate thestereochemistry around the stereogenic centers present in the products,as well as the mechanism by which each product is formed.