Please dont copy here in Bartleby • Distinguish between a purine, pyrimidine, nucleoside, nucleotide, polynucleotide, and double helix. How do these structures differ in DNA and RNA?
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- Discuss the structural significance of complementarity in DNAand in RNA.Tabulate the main structural features of DNA and RNA. In one sentence, point out the salient difference(s) if any in the structures of these nucleic acids?Compare and contrast the structure of DNA and RNA. Be sure to describe each of the three components of a nucleotide for both DNA and RNA along with the types of bonds formed between the components. In addition, explain: how the nucleotides link together to form each molecule, why the prime ends are labeled 5’ and 3’, what antiparallel is, what phospodiester linkages are and what complementary base pairing is.
- If the DNA molecule read its complementary strand as: TACGATCCGAACCAAACT, how would the m-RNA read the above template? Identify the codons of the m-RNA. Identify the amino acids read by the t-RNA. What polypeptide is formed after hydrolysis when amino acids separate from t-RNA? Construct the primary structure of the said polypeptide in trans configuration and write its nomenclature.Can you: describe the 2 D and 3 D structure of DNA including the bonding that takes place?Compare the structural features of a double-stranded RNA structurewith those of a DNA double helix.
- 1) a) Sketch an A-form helix and a B-form helix, highlighting the differences between them. Indicate the bases and backbone as lines. Label the major and minor grooves. 2) Sketch a ribose in the pucker that is expected in RNA. 3) Sketch a 2’ deoxyribose in the pucker that is expected in DNA. 4) Draw a GCG triplet (GC Watson-Crick), with perfect geometry. Draw the bases only, with dR’s at the N-9 positions of the purines (Gs) and at the N1 positions of the pyrimidine (C)Explain how the functions of DNA emerge from the structure of its monomers and its antiparallel, doublehelical, three-dimensional structure.What are the complementary base pairs in DNA-RNA interactions? Answer format: Base 1(one letter symbol)-Base 2 (one letter symbol, or B-B*(hypothetical N-base) In the lengthening of a polynucleotide chain, which type of nucleotide subunit (name please not the formula) would bond to its 3’ end? How many 3’,5’-phosphodiester linkages are present in a tetranucleotide segment of a nucleic acid?
- Compare the structural features of a double-stranded RNA moleculewith those of a DNA double helix.Given the following eukaryotic DNA strand, transcribe and translate the DNA into a polypeptide using the 3’ – 5’ strand as the template. use drawings, diagrams, colours and annotations to describe how the DNA strand will be synthesized into a functional protein. 5’ - TATAAAAASSMSBMDATGSBDCCMBDBAATBSMDSTGTGTCCTMSBAG – 3’ (KEY: The letters SBMD are “made up” nucleic acids that depict non-coding regions in the DNA, hypothetically S pairs with B and M pairs with D).Compare and contrast the properties of DNA polymerase and RNA polymerase. Drag the appropriate items to their respective bins. can proofread using a 3'-to-5' exonuclease activity polymerize in a 5'-to-3' direction Only RNA can initiate strand synthesis catalyze phosphodiester bond formation to polymerize nucleotides into nucleic acids Only DNA use deoxyribonucleotide triphosphates as substrates can only extend an existing strand Both Reset Help dependent on a DNA sequence template use ribonucleotide triphosphates as substrates