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Options
bacitracin,
vancomycin,
polymyxin,
none of these is correction
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- Is the regulation shown (denoted by?) positive or negative regulation? Explain why the type of regulation shown here is advantageous for the cellThe small, monomeric protein Rho has acquired a mutation by which it is constitutively activated and evenly distributed along with the cytoplasmic leaflet of the plasma membrane. Describe the effects this would have on cell crawling. A complete answer will include a description of normal Rho distribution and activation, an explanation of Rho function in cell crawling, and a thoughtful argument for an overall effect of the mutation on cell crawling that is based on the specific roles of Rho.The figure above shows the organization of a protein that will eventually reside in the plasma membrane. The boxes labeled 1 and 2 represent membrane-spanning sequences and the arrow represents a site of action of signal peptidase. Which of the following statements must be TRUE about this protein? O a) Most of this protein will project from the cytosolic side of the membrane. O b) The mature version of this protein will span the membrane twice. c) This is a multi-pass membrane protein. O d) The mature version of this protein will span the membrane once.
- Atherosclerosis can obstruct or block flow in arteries, including those that provide oxygenated blood to the heart. Elevated levels of [ Select ] ["LDL, and VLDL", "HDL"] are associated with atherosclerosis, most likely because of their role in delivery of lipids to peripheral tissues and cells. Smooth muscle cells are recruited to the site of damage, where they [ Select ] ["induce apoptosis of endothelial cells", "proliferate"] , hence expanding the extent of the lesion.MPF plays an important role during the regulation of the cell cycle. give examples that will support this statement.Amoeboid cells that migrate through our tissues, such as the class of white blood cells known as neutrophils, often do so in a directed manner, triggered, for instance, by chemical signals released by pathogens such as bacteria. Directed migration in response to a chemical stimulus is known as chemotaxis. Part of an efficient chemotactic response is the ability of cells to polarize. As is the case with our structurally-polar polymers like F-actin or microtubules, polarization here refers to an asymmetry in the cells, rather than an electrical charge. In this case, it involves one part of the cell becoming the “front” (or leading edge) and another the rear. In a well-polarized, migrating cell, it’s been observed that an active form of Rac (which, in turn, can activate ARP 2/3) is concentrated towards the front of the cell, whereas an active form of Rho (which, in turn, can activate formin, inhibit ADP, and activate myosin II) is found toward the rear of the cell. Based on your…
- Amoeboid cells that migrate through our tissues, such as the class of white blood cells known as neutrophils, often do so in a directed manner, triggered, for instance, by chemical signals released by pathogens such as bacteria. Directed migration in response to a chemical stimulus is known as chemotaxis. Part of an efficient chemotactic response is the ability of cells to polarize. As is the case with our structurally-polar polymers like F-actin or microtubules, polarization here refers to an asymmetry in the cells, rather than an electrical charge. In this case, it involves one part of the cell becoming the “front” (or leading edge) and another the rear. In a well-polarized, migrating cell, it’s been observed that an active form of Rac (which, in turn, can activate ARP 2/3) is concentrated towards the front of the cell, whereas an active form of Rho (which, in turn, can activate formin, inhibit cofilin/ADP, and activate myosin II) is found toward the rear of the cell. Based on your…You plan to synthesize a peptide to be used as a vaccine to treat melanoma, a particularly aggressive form of skin cancer. Normally, gp100, a protein on the surface of melanocytes, activates cell growth when it is bound by its ligand. Activation of the growth pathway depends on the presence of threonine in the ligand. The effective peptide vaccine will mimic the natural ligand, but won’t cause cell growth and division. Below is the sequence of the natural ligand: LDMKTAG In order to ensure your newly designed peptide vaccine does not cause cell growth upon binding, you must substitute the Threonine residue at position 5. What amino acid would you replace it with, bearing in mind that the peptide should still be similar enough to bind to the gp100 protein in the surface of melanocytes. Explain your choice. Your vaccine will be administered as a topical cream, and you require your peptide to have an overall neutral charge in order to be functional. At what pH should you formulate…Please help me with this question. More than one answer may be correct. The cis golgi compartment ______. Options: A) is a convenient place to store tools in small cars. B) uses clathrin as a coating protein to send vesicles to the medial compartments. C) sends proteins to their proper destination. D) is continuous with the trans compartment. E) adds specific signal to proteins destine for the lysosomes.
- "Like the lumen of the ER, the interior of the nucleus is topologically equivalent to the outside of the cell" is true or false.For any antibiotic compounds that don’t appear to inhibit translation of proteins from the ribosome, purpose another potential mechanism whereby this class of antibiotic might be able to act (outside of cell wall/membrane formation). Explain in deatil.You’ve made a 25 mM stock of colchicine (a tubulin inhibitor; dissolved in distilled water), which you’d like to use to study the effect of tubulin on phagocytosis in T.pyriformis. Based on published research articles that you’ve read, you’d like to preincubate T. pyriformis with colchicine at a final, effective concentration of 75 µM. Assuming you need 40 µL of the cell+colchicine mixture for your experiment, please explain how you can use your 25 mM solution of colchicine, T. pyriformis cells, and distilled water to create your cell+colchicine mixture.