Of the steps illustrated how many are unidirectional? Identify the substrate and product of each of these steps. Identify the three enzymes that are likely to be regulated in glycolysis? How did you make this determination. Glycogen synthase is an enzyme that catalyzes the synthesis of glycogen from glucose. Glucose 6 phosphate activates glycogen synthase by allosteric regulation. Illustrate and describe how this allosteric modulation is likely to occur?

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter18: Glycolysis
Section: Chapter Questions
Problem 9P: Comparing Glycolysis Entry Points for Sucrose Sucrose can enter glycolysis by either of two routes:...
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  1. Of the steps illustrated how many are unidirectional? Identify the substrate and product of each of these steps.
  2. Identify the three enzymes that are likely to be regulated in glycolysis? How did you make this determination.
  3. Glycogen synthase is an enzyme that catalyzes the synthesis of glycogen from glucose. Glucose 6 phosphate activates glycogen synthase by allosteric regulation. Illustrate and describe how this allosteric modulation is likely to occur?
  4. Glycogen phosphorylase, an enzyme that catalyzes the breakdown of glycogen to form glucose, is active when a phosphate group is added. This is an example of enzyme regulation by ____________________________. 

 

 

ctions: On
Names:
The following is an illustration of the glycolysis pathway:
Accessibility: Investigate
Dihydroxyacetone
phosphate
HO
1
3
4
6
8
9
Glucose
k
Hexokinase ATP
Glucose 6-phosphate
Phosphoglucose
isomerase
Triose
5 phosphate Glyceraldehyde
isomerase.
3-phosphate
(2 molecules)
10
Fructose 6-phosphate
$1
Phosphofructo- ATP
kinase-1 ADP
Fructose 1,6-bisphospha
Aldolase
7 Phosphoglycerate
Glyceraldehyde 2 NAD+ +
3-phosphate 2 NADH +
dehydrogenase
1,3-Bisphosphoglycerat
(2 molecules)
1
kinase 2 ATP
3-Phosphoglycerate
(2 molecules)
F7
ADP
Phosphoglycero-
mutase
2 ADP
2-Phosphoglycerate
(2 molecules)
Enolase
2 H₂O
Phosphoenolpyruvate
(2 molecules)
Pyruvate 2 ADP
kinase 2 ATP
8¹
Pyruvate
(2 molecules)
DELL
D
F9
Styles
W
prt sc
F10
home
Transcribed Image Text:ctions: On Names: The following is an illustration of the glycolysis pathway: Accessibility: Investigate Dihydroxyacetone phosphate HO 1 3 4 6 8 9 Glucose k Hexokinase ATP Glucose 6-phosphate Phosphoglucose isomerase Triose 5 phosphate Glyceraldehyde isomerase. 3-phosphate (2 molecules) 10 Fructose 6-phosphate $1 Phosphofructo- ATP kinase-1 ADP Fructose 1,6-bisphospha Aldolase 7 Phosphoglycerate Glyceraldehyde 2 NAD+ + 3-phosphate 2 NADH + dehydrogenase 1,3-Bisphosphoglycerat (2 molecules) 1 kinase 2 ATP 3-Phosphoglycerate (2 molecules) F7 ADP Phosphoglycero- mutase 2 ADP 2-Phosphoglycerate (2 molecules) Enolase 2 H₂O Phosphoenolpyruvate (2 molecules) Pyruvate 2 ADP kinase 2 ATP 8¹ Pyruvate (2 molecules) DELL D F9 Styles W prt sc F10 home
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  1. Glycogen phosphorylase, an enzyme that catalyzes the breakdown of glycogen to form glucose, is active when a phosphate group is added. This is an example of enzyme regulation by ____________________________. 
ctions: On
Names:
The following is an illustration of the glycolysis pathway:
Accessibility: Investigate
Dihydroxyacetone
phosphate
HO
1
3
4
6
8
9
Glucose
k
Hexokinase ATP
Glucose 6-phosphate
Phosphoglucose
isomerase
Triose
5 phosphate Glyceraldehyde
isomerase.
3-phosphate
(2 molecules)
10
Fructose 6-phosphate
$1
Phosphofructo- ATP
kinase-1 ADP
Fructose 1,6-bisphospha
Aldolase
7 Phosphoglycerate
Glyceraldehyde 2 NAD+ +
3-phosphate 2 NADH +
dehydrogenase
1,3-Bisphosphoglycerat
(2 molecules)
1
kinase 2 ATP
3-Phosphoglycerate
(2 molecules)
F7
ADP
Phosphoglycero-
mutase
2 ADP
2-Phosphoglycerate
(2 molecules)
Enolase
2 H₂O
Phosphoenolpyruvate
(2 molecules)
Pyruvate 2 ADP
kinase 2 ATP
8¹
Pyruvate
(2 molecules)
DELL
D
F9
Styles
W
prt sc
F10
home
Transcribed Image Text:ctions: On Names: The following is an illustration of the glycolysis pathway: Accessibility: Investigate Dihydroxyacetone phosphate HO 1 3 4 6 8 9 Glucose k Hexokinase ATP Glucose 6-phosphate Phosphoglucose isomerase Triose 5 phosphate Glyceraldehyde isomerase. 3-phosphate (2 molecules) 10 Fructose 6-phosphate $1 Phosphofructo- ATP kinase-1 ADP Fructose 1,6-bisphospha Aldolase 7 Phosphoglycerate Glyceraldehyde 2 NAD+ + 3-phosphate 2 NADH + dehydrogenase 1,3-Bisphosphoglycerat (2 molecules) 1 kinase 2 ATP 3-Phosphoglycerate (2 molecules) F7 ADP Phosphoglycero- mutase 2 ADP 2-Phosphoglycerate (2 molecules) Enolase 2 H₂O Phosphoenolpyruvate (2 molecules) Pyruvate 2 ADP kinase 2 ATP 8¹ Pyruvate (2 molecules) DELL D F9 Styles W prt sc F10 home
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