O2 is a competitive inhibitor of the hydrogenase enzyme that catalyzes the conversion between protons & electrons and H2. The inhibition by O2 is irreversible, permanently destroying the enzymatic activity. (a) Describe the relevant reactions that take place when a hydrogenase catalyzes H2 production in the presence of O2. (b) Derive the rate equation for v as a function of [E], [H+] and [O2], assuming that the electron concentration/delivery is not rate-limiting.

O2 is a competitive inhibitor of the hydrogenase enzyme that catalyzes the conversion between protons & electrons and H2. The inhibition by O2 is irreversible, permanently destroying the enzymatic activity. (a) Describe the relevant reactions that take place when a hydrogenase catalyzes H2 production in the presence of O2. (b) Derive the rate equation for v as a function of [E], [H+] and [O2], assuming that the electron concentration/delivery is not rate-limiting.

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter23: Fatty Acid Catabolism

Section: Chapter Questions

Problem 21P: Using the ActiveModel for enoyl-CoA dehydratase, give an example of a case in which conserved...

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