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Metabolic acidosis. As we will see later in the course, pathological conditions arise where the blood pH falls because of excess acid production, a condition called metabolic acidosis. Excess protons in the blood decrease the amount of HCO3− and thus reduce the buffering capacity of blood. A rapid drop in pH could lead to death. Normal values for blood are: pH = 7.4, [HCO3−] = 24.0 mM, [CO2] = 1.20 mM.✓ 6   (a) If a patient has a blood pH = 7.03 and [CO2] = 1.2 mM, what is the [HCO3−] in the patient’s blood? The pKa of HCO3−= 6.1.   (b) Suggest a possible treatment for metabolic acidosis.   (c) Why might the suggestion for part (b) be of benefit to middle-distance runners?

Metabolic acidosis. As we will see later in the course, pathological conditions arise where the blood pH falls because of excess acid production, a condition called metabolic acidosis. Excess protons in the blood decrease the amount of HCO3− and thus reduce the buffering capacity of blood. A rapid drop in pH could lead to death. Normal values for blood are: pH = 7.4, [HCO3−] = 24.0 mM, [CO2] = 1.20 mM.✓ 6   (a) If a patient has a blood pH = 7.03 and [CO2] = 1.2 mM, what is the [HCO3−] in the patient’s blood? The pKa of HCO3−= 6.1.   (b) Suggest a possible treatment for metabolic acidosis.   (c) Why might the suggestion for part (b) be of benefit to middle-distance runners?

General Chemistry - Standalone book (MindTap Course List)
General Chemistry - Standalone book (MindTap Course List)
11th Edition
ISBN:9781305580343
Author:Steven D. Gammon, Ebbing, Darrell Ebbing, Steven D., Darrell; Gammon, Darrell Ebbing; Steven D. Gammon, Darrell D.; Gammon, Ebbing; Steven D. Gammon; Darrell
Publisher:Steven D. Gammon, Ebbing, Darrell Ebbing, Steven D., Darrell; Gammon, Darrell Ebbing; Steven D. Gammon, Darrell D.; Gammon, Ebbing; Steven D. Gammon; Darrell
Chapter16: Acid-base Equilibria
Section: Chapter Questions
Problem 16.125QP: A solution made up of 1.0 M NH3 and 0.50 M (NH4)2SO4 has a pH of 9.26. a Write the net ionic...
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Metabolic acidosis. As we will see later in the course, pathological conditions arise where the blood pH falls because of excess acid production, a condition called metabolic acidosis. Excess protons in the blood decrease the amount of HCO3− and thus reduce the buffering capacity of blood. A rapid drop in pH could lead to death. Normal values for blood are: pH = 7.4, [HCO3−] = 24.0 mM, [CO2] = 1.20 mM.✓ 6

 

(a) If a patient has a blood pH = 7.03 and [CO2] = 1.2 mM, what is the [HCO3−] in the patient’s blood? The pKa of HCO3−= 6.1.

 

(b) Suggest a possible treatment for metabolic acidosis.

 

(c) Why might the suggestion for part (b) be of benefit to middle-distance runners?

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