Malate synthase in E. coli catalyzes the reaction Acetyl-CoA + glyoxylate + H₂O malate + CoA-SH + H+ The experimentally measured Km for acetyl-CoA is 9 x 10-6 M. In a growing culture of E. coli, the measured concentration of acetyl-CoA is 6 x 10-4 M. Complete the passage based on these experimental results. Malate synthase is glyoxylate, the reaction rate is limited by with the substrate acetyl-CoA. If [glyoxylate] is below the Km for at Vmax. and malate synthase

Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter31: Immunochemistry
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Malate synthase in E. coli catalyzes the reaction
Acetyl-CoA + glyoxylate + H₂O
malate + CoA-SH + H+
The experimentally measured Km for acetyl-CoA is 9 x 10-6 M. In a growing culture of E. coli, the measured concentration
of acetyl-CoA is 6 x 10-4 M.
Complete the passage based on these experimental results.
Malate synthase is
glyoxylate, the reaction rate is limited by
with the substrate acetyl-CoA. If [glyoxylate] is below the Km for
at Vmax.
and malate synthase
Transcribed Image Text:Malate synthase in E. coli catalyzes the reaction Acetyl-CoA + glyoxylate + H₂O malate + CoA-SH + H+ The experimentally measured Km for acetyl-CoA is 9 x 10-6 M. In a growing culture of E. coli, the measured concentration of acetyl-CoA is 6 x 10-4 M. Complete the passage based on these experimental results. Malate synthase is glyoxylate, the reaction rate is limited by with the substrate acetyl-CoA. If [glyoxylate] is below the Km for at Vmax. and malate synthase
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