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- Naloxone is sometimes added to PO phenanthrene formulations to reduce injection abuse while retaining pain relief when used properly. Naltrexone is not used in this way because naltrexone: 1. is orally bioavailable 2. will reduce conversion of the opioid pro-drug 3. will cross the blood brain barrier. 4. has a longer half-life 5. should only be used for opioid maintenance therapyBriefly discuss the “Six Rights” associated with safe medication administrationWhich of the following are true statements? [Select all that apply.] 1. Opioid drugs are much safer than most prescription drugs. 2. There is strong evidence to support the use of opioids for chronic noncancer pain. 3. Abuse of opioid drugs presents a serious public health problem. 4. The financial success of OxyContin is in large part due to aggressive marketing by its manufacturer.
- 2.) How can these pathological factors listed below affect drug effects? Explain each. - Gi disorders - Vascular disorders - Liver dysfunction - Kidney dysfunctionWhich of the following are true statements? [Select all that apply.] The financial success of OxyContin is in large part due to aggressive marketing by its manufacturer. Opioid drugs are much safer than most prescription drugs. There is strong evidence to support the use of opioids for chronic noncancer pain. Abuse of opioid drugs presents a serious public health problem.1. What is the medical science concerned with the use of drugs in the treatment of disease? * a Pharmacotherapeutics b Pharmacology c Pharmacoepidemiology Pharmacognosy d Pharmacogenetics 2 Which of the following is ACCURATE about Reboxetine? * a MAO inhibitor b Noradrenaline reuptake inhibitor c Adrenergic agonist d Cholinergic agonist e Selective serotonin reuptake inhibitor 3 In Graded Dose-Response, which of the following parameters refers to the dose producing 50% of the maximum response? * a Potency b LD50 c Efficacy d Ceiling dose e ED50 4 Which of the following statements best describe a partial agonist? * a Interacts with more than one receptor type b Blocks the effect of the antagonist c Cannot produce the full effect even at high doses d Has low potency but high efficacy. e Has affinity but lacks efficacy 5 Which drug promotes transient muscle fasciculation followed by muscle paralysis that is not reversed by Neostigmine? * a Hyoscyamine b Rocuronium c Succinylcholine d…
- there's been several ideas for newer opioid medications that may reduce abuse liability, is there any new medications being developed that would be more difficult to abuse that can help abusers of opioids?Receptor 8.0 1 Drug A Receptor 7.8 2 Receptor 3 Drug B 8.5 PA value 5.2 6.4 Drug C 3.1 Drug D 6.5 10.5 3.9 6.5 4.5 9.7 Drug E 9.9 7.2 3.5 Which of these drugs is most likely to cause side-effects?Which of the following medications is not one of the sulfonylurea derivatives?A. GliclazideB. GlimepirideC. GliquidoneD. GlibenclamideE. Avandia
- Most commonly available Non-prescription Proton Pump Inhibitor (PPI) medications: Brand Name of the Drug Name of the Drug Dosage Potential Side Effects 1. 2. 3. 4. 5. 6. 7. 8. 9. 10.Psychoactive drugs work by, EXCEPT: blocking receptors (antagonists) blocking reuptake (antagonists) blocking enzymatic degradation of neurotransmitters blocking the impulsivity to take drugs5. Which of the following drugs is/are metabolized to a compound that will continue to have significant sedative and hypnotic effect? H3C OH -OH CI CI 1. Oxazepam 2. Temazepam H3C HO- 3. Lorazepam 4. Midazolam H3C 5. Diazepam