Give typed full explanation In unit 1 we learned about the CFTR gene that codes for a chloride channel that does not functionnormally in patients with Cystic Fibrosis. Which of the following may also lead to Cystic Fibrosis?O methylation of the CFTR promoterO a mutation in a CFTR enhanceran overactive repressor protein that binds to a CFTR silencerO increased expression of a miRNA that targets the CFTR mRNAO all of the above

Cystic Fibrosis (CF) is a genetic disorder that is caused by mutations in the CFTR gene. This gene…

Answered: In unit 1 we learned about the CFTR…

Phlebotomy Essentials

6th Edition

ISBN:9781451194524

Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Chapter1: Phlebotomy: Past And Present And The Healthcare Setting

Section: Chapter Questions

Problem 1SRQ

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Which of the following is least related to the other items? Group of answer choices inducer repressor operator enhancers 2. A scientist observing a cell during gene expression would be able to easily distinguish it as a prokaryotic cell by which of the following observations? Group of answer choices as soon as the DNA introns are removed from the template after the 5' caps are converted to mRNA after a transcription initiation complex has been formed during transcription once the pre-mRNA has been converted to mRNA
Part A Which of the following could be used to turn on a regulon (composed of multiple genes and operons) in a bacterium? There are multiple correct answers. You must select all correct options1 O use riboswitches that all respond to the same molecule O activate an alternative RNA polymerase mutate (change) a promoter sequence V activate an alternative sigma factor O specifically degrade one kind of repressor protein Submit Previous Answers Request Answer X Incorrect; Try Again; 3 attempts remaining
1. (a) Tryptophan-repressor complex binds to operator Gene is switched ON Gene is switched OFF Does NOT affect the gene expression (b) Operator is not bound with the repressor Gene is switched ON Gene is switched OFF Does NOT affect the gene expression
Wilms tumor 1, or nephroblastoma, is caused by mutations in the WT1 gene, which encodes a transcription factor. You have identified a novel variant in WT1: Arg422Pro. You have control cells and cells that have been engineered to carry the homozygous WT1 p.Arg422Pro mutation. You want to assess effects of this mutation on a variety of endpoints. For each endpoint listed below, choose the one technique is best suited to answer the question. Choose from: array CGH, qRT-PCR, qPCR, RNA-seq, FISH, in situ hybridization, western blot, immunostaining, WT1 ChIP-seq, WT1 ChIP-PCR, ATAC-seq, 3C Endpoint Technique? WT1 protein amount (quantitative) Western blot WT1 protein binding to all enhancers, genome-wide Chip-seq WT1 mRNA amount (quantitative) WT1 protein subcellular localization Quantitative assessment of all mRNAs in these cells (genome-wide) RNAseq Chromatin interactions between a specific WT1 chromatin binding site (identified above)…
Which of the following is least related to the other items? Group of answer choices inducer repressor operator enhancers regulator 2. Which of the following would best ensure that a kidney cell and a liver cell from the same person would express different genes? Group of answer choices differences in introns unique sets of transcription factors they only have specific genes unique sets of promoters
In the above E. coli cell, with high glucose and low lactose levels, what happens at the operator? low lactose causes activation of a repressor protein, allowing it to detach from the operator low lactose causes inactivation of a repressor protein, allowing it to detach from the operator low lactose causes activation of a repressor protein, allowing it to bind to the operator low lactose causes inactivation of a repressor protein, allowing it to bind to the operator all of the above
Which of the following small GTP-binding proteins does NOT play a role in cell migration during chemotaxis? O Cap Z Rho Cdc42 O All of the listed GTPases play a role in cell migration O Rac ◆ Previous
Which of the following accurately describes the function of HOTAIR? It is a long non-coding RNA that regulates transcription of target genes by recruiting the chromatin modification complexes LSD1 and PRC2 It is a scaffold RNA that brings crRNA and CAS9 proteins together for viral defense It is a miRNA that regulates the transcription of target genes by recruiting chromatin the chromatin modification complexes LSD1 and PRC2 It is an SIRNA that regulates the transcription of target genes by repressing their translation by targeting them for degradation It is a miRNA that regulates the transcription of target genes by repressing their translation It is an SIRNA that regulates the transcription of target genes by repressing their translation It is a miRNA that regulates the transcription of target genes by repressing their translation by targeting them for degradation
The following diagram depicts the elements at the: Ac TTC g99 Ea cgcc tata an! ATT BRE TATA box Inr DPE (TBP) TFIIB TEIID Promoter Enhancer O transcribed gene O Silencer
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in a fat cell what is the result of activation of genes by PPAR gamma/activator proteins binding? what is the result of inactivation of genes when PPAR gamma and repressor are bound ?

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