In the figures below, observe the biosynthesis of scopolamine and its intermediates. THE scopolamine is formed by the fusion of two biosynthetic pathways. One derived from L-ornithine and the other from L-phenylalanine. In the bold rectangles are the respective key enzymes that catalyze each of the biosynthesis steps. Scopolamine is a competitive, non-selective muscarinic receptor antagonist drug acetylcholine receptor antagonist (mACHR) giving rise to important pharmacological effects, such as by example antispasmodic action in the gastrointestinal tract. Answer: 1) Does scopolamine belong to which chemical class/subclass of natural products? 2) This substance can
In the figures below, observe the biosynthesis of scopolamine and its intermediates. THE scopolamine is formed by the fusion of two biosynthetic pathways. One derived from L-ornithine and the other from L-phenylalanine. In the bold rectangles are the respective key enzymes that catalyze each of the biosynthesis steps. Scopolamine is a competitive, non-selective muscarinic receptor antagonist drug acetylcholine receptor antagonist (mACHR) giving rise to important pharmacological effects, such as by example antispasmodic action in the gastrointestinal tract. Answer: 1) Does scopolamine belong to which chemical class/subclass of natural products? 2) This substance can
Chapter11: Measuring Insulin Dosages
Section: Chapter Questions
Problem 1.21P
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In the figures below, observe the biosynthesis of scopolamine and its intermediates. THE scopolamine is formed by the fusion of two biosynthetic pathways. One derived from L-ornithine and the other from L-phenylalanine. In the bold rectangles are the respective key enzymes that catalyze each of the biosynthesis steps. Scopolamine is a competitive, non-selective muscarinic receptor antagonist drug acetylcholine receptor antagonist (mACHR) giving rise to important pharmacological effects, such as by example antispasmodic action in the gastrointestinal tract.
Answer:
1) Does scopolamine belong to which chemical class/subclass of natural products?
2) This substance can be extracted from different plant species, such as: Atropa,
Duboisia, Hyoscyamus, Mandragora and Datura. What is the botanical family of these species?
3) What are the biogenetic origins (biosynthetic pathways) of ornithine and phenylalanine?
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