In a study that is interested in the possible association between smoking (exposure) and coronary heart disease (CHD) disease. If the investigators begin with 800 people with CHD (cases) and compare them with 1600 controls (people without CHD) is this a case control investigation? Suppose 448 of the 800 cases were smokers and 256 were nonsmokers. Of the 1600 controls, 704 were smokers and 896 were nonsmokers. What is the measure of association in this investigation? How could this be calculated? What does this mean?

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In a study that is interested in the possible association between smoking (exposure) and coronary heart disease (CHD) disease. If the investigators begin with 800 people with CHD (cases) and compare them with 1600 controls (people without CHD) is this a case control investigation?

Suppose 448 of the 800 cases were smokers and 256 were nonsmokers. Of the 1600 controls, 704 were smokers and 896 were nonsmokers.

  1. What is the measure of association in this investigation?
  2. How could this be calculated?
  3. What does this mean?
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