In a rare condition in which the immediate release of neurotransmitter is affected, a mutation in gene would be detected. | a) syntaxin b) synaptotagmin c) syanptobrevin d) synuclein
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- Synaptic vesicles release into the synapse to give the message to the post synaptic neuron?Multicellular organisms:a) are larger in size than unicellular organisms b) can do a wider variety of functionsFor a stroke patient with hypertension who is a candidate for recombinant tissue plasminogen activator rt pa which blood pressure control strategy is appropriate?Sort the following steps of GPCR signal propagation (you may not use all the steps): A) Dephosphorylation of GPCR B) G protein dissociation to adenylate cyclase and GTP binds to the G protein C) Ligand binding to GPCR D) G protein dissociation from GPCR and GDP binds to the G protein E) Synthesis of CAMP F) Activation of PKA G) G protein association to adenylate cyclase H) G protein dissociation from GPCR and GTP binds to the G protein O F, C, H, F, B OC OB, D, A, E, H O C, H, G, E, F OA, G, H, B, EWhen the inhibitory Ga (Gia) protein is mutated and increases its intrinsic GTPase activity, a) Adenylate cyclase become more active b) Gia becomes more active c) Both a and b d) Neither a or b
- 7. A) What effect does the compound GppNHp, when applied to the inside of a cell during whole cell patch clamp recording, have on Cav2 channels at presynaptic terminals? B) What is the mechanism by which this compound affects G-protein signaling and Ca√2 channel activity? B. A.The p75 receptor differs from Trk receptors in that it a) can promote cell death. b) has high affinity for all neurotrophins. c) only binds a particular type of neurotrophin. d) can bind NGF to promote cell survival.In rats, the spinal nucleus of the bulbocavernosus undergoes greater a) apoptosis; females b) apoptosis; males c) neurogenesis; males d) neurogenesis; females in
- With protein kinase-mediated molecular switches, downstream target molecules are typically activated by ... a) being phosphorylated b) binding to ATP c) the action of a phosphataase d) hydrolysis of GTP e) binding to GTPA) Please explain what a G protein coupled receptor is. Please explain how G protein interacts with this receptor. B) Please explain the kind of reactions that follow binding a specific ligand to a G protein coupled receptor. What do these reactions do in the cell? C) How do these reactions work in the cell. What is the function of these reactions in the cell? How do the reactions proceed?Synaptic transmission requires a vast number of molecular interactions taking place on both ends of synaptic cleft. Write down each of the below molecules that plays a role in (or events caused by a mechanism in): (A) PRE-synaptic axon terminal only; (B) POST-synaptic dendrite only; (C) can either be in PRE-synaptic or POST-synaptic terminal site: (D) Neither PRE-synaptic nor POST-synaptic terminal site a) Clathrin [Select] b) Endocannabinoid synthesis [Select] c) EPSP [Select] d) Myelin sheath [Select] e) Voltage-gated Ca2+ channel [Select] f) Curare [Select] g) Miniature endplate potentials [Select] h) Synaptotagmin [Select] i) Axon hillock [Select] < < < <
- 12. Which statement regarding cell-surface receptors is correct? A) lon-channel-coupled receptors alter the membrane potential directly by changing the permeability of the plasma membrane. B) G-protein-coupled receptors are polypeptides with seven transmembrane domains. C) After binding their ligand, G-protein-coupled receptors interact with intracellular GTP-binding proteins, later initiating signal transduction events. D) All of the above E) None of the above Answer: Explanation:Based on studies, synaptotagmin is a crucial protein anchored to the vesicle and it is activated by binding to a) A RIM-BP protein anchore b) phosphorylation c) A SNAP-25 complex d) five Ca2+ via its C2A and C2B domains4:32 120-201 FA22 Homework 02 2.docx 10. When a primary signal needs to be sent to most cells throughout a multicellular organism, the signal most suited for this is a AG) neurotransmitter. AH) hormone. AI) dissolved gas. AJ) transcription factor. AK) translation elongation factor Answer: Explanation: 5G 100 AM) the steroid hormones AN) tyrosine-derived epinephrin and norepinephrin AO) serotonin and melatonin (tryptophan-derived mammalian neurotransmitters) 11. Hydrophobic primary messengers usually cause molecular changes leading to modifications in metabolism. Examples of hydrophobic primary messengers are Explain what are their general chemical properties. AL) thyroxine (tyrosine-derived hormone) and insulin (a small peptide hormone) AP) auxins (tryptophan-derived plant hormones) Answer: Explanation: 12. Which statement regarding cell-surface receptors is correct? AQ) lon-channel-coupled receptors alter the membrane potential directly by changing the permeability of the plasma…