III. Protein: QQICIMFELTQISS Predict the products of the following reactions with the protein given, if there is none, write NO RXN. Also indicate, if the reaction is fast or slow. 9.) KOH/Pb(CH;CO0)2 10.) Glyoxilic Acid/Conc. H2SO4
Q: Match each charge form of alanine under the pH conditon where it would be the predominant form. The…
A: Alanine is an α-amino acid that is needed for protein biosynthesis. It is non-essential for humans…
Q: 1 What is the dominant biochemical activity or molecular interaction that your protein is predicted…
A: Amyloid-beta precursor protein is single pass transmembrane protein with large extracellular domain…
Q: TFQFPFAEQL EKVAEQFPTF QILNEEGEVV NEEAMPELSD EOLKELMRRM : (amino h (amino) (amino i (amino amg…
A: These six amino acid residues are split between two subunits. Together, they form a BASIC tunnel…
Q: 7. a) Draw a model complex structure for vitamin B12 and give a name to the complex. b) Define the…
A: Micronutrients are defined as the type of nutrients that are needed for the body in less amount. The…
Q: (iv) Consider the molecule 1 being derivatized to yield molecule 2. How would you expect AG for the…
A: Biomolecules are the molecules involved in several biochemical pathways and also part of important…
Q: 1. a.Draw the fisher projection and a skeletal diagram of: An aldohexose and deoxy-ketopentose b.…
A: Sugar molecules are of two types depending upon the presence of aldehyde group or ketone group in…
Q: (b) Account for the observation that the trans-,2-dibenzoylethylene appears yellow in color, whereas…
A: 1,2-dibenzoylethylene can exist in two forms, trans and cis due to lack of rotation about it's C-C…
Q: 1. Using Hydrophobic interaction chromatography, the protein that will be eluted FIRST is
A: Hydrophobic interactions are one typeof bonding interactions that are present between water and…
Q: Describe the compound below B. monoterpene precursor O A. starting material for fatty acid…
A: Biomolecules are engaged in a variety of biological and chemical processes in the human body and are…
Q: Activity 2: Enzyme Structure 1. Use the following terms to label the diagram below: Prodect…
A: Several metabolic pathways exist in the human body. Each pathway enables catalysis of the chemical…
Q: B: For each of the following reaction types, find a step in a pathway that is an example and for…
A: Proteins that catalyze biochemical reactions inside living organisms are called enzymes. Depending…
Q: 1. The antibiotics puromycin and erythromycin are known inhibitors of protein synthesis. (a)…
A: Puromycin - It ia an aminonucleoside antibiotics which occurs naturally and it inhibits the…
Q: b) The above molecule may be further converted into a polymer with similar molecular structure to…
A: The molecule given in the question is named the molecule" 5-hydroxymethyl-2-furaldehyde or…
Q: Identify. Examine the following four amino acids (A-D): Co0 "H,N- CH "H,N CH "H;N-CH "H,N CH CH2 CH2…
A: Amino acids are the building block for proteins/peptides. They are linked to one another by a…
Q: 2. a. How do the majority of proteins that exist outside cells get outside cells? Explain the…
A: There are different proteins inside the living system that needs to be sent to different parts in a…
Q: a) Identify the five amino acids. b) Draw the three dissociation reactions for one of them.
A: Amino acids are organic compounds with functional groups namely carboxyl and amino. At low pH, amino…
Q: 1. What are the pK,s associated with a typical aliphatic carboxylic acid? A typical aliphatic amine?…
A: Amino acid have two functional groups namely-carboxyl group and amino group. If both groups are…
Q: 5. Write a balanced equation for each of the processes in Part A. Remember to include heat on the…
A: Reaction A: It is a reaction between ammonium chloride and water since heat is being consumed in the…
Q: 7. Which of the following is true of water in the hydration layer of proteins? a. It has a lower AS…
A: Note : Hi! Thank you for the question. We are authorized to answer one question at a time. Since you…
Q: 3. Determine the primary structure of pentadecapeptide X, based on the following results. A).…
A: Determination of protein primary structure is done by degradation with different enzymes which have…
Q: Given a dipeptide Gly-Val, Gly: Pk,=2.34; pkK,=9.60 Val: Pk,=2.32; pK,=9.62 a. draw the protonic…
A: The peptides are biomolecules formed of more than one amino acid joined through an amide bond. The…
Q: 1. The use of natural proteins as drugs requires compliance with certain storage and use conditions,…
A: Protein: Polymer of amino acid joined together through peptide bond removing water in a process…
Q: what is the cost the cost in total d carbon chain stearic acid?
A: Fatty Acid Oxidation (Beta-oxidation) To generate energy from fatty acids, they must be oxidized.…
Q: Experimental results describing a protein's amino acid composition are useful for estimating the…
A: Proteins are biological macromolecules composed of amino acids linked together by peptide bonds. The…
Q: and s stand (A) Vitamin 012 can be reduced to forms B12, and B12, What is the abbreviationr for? (B)…
A: Vitamins are vital nutrients required for the normal functioning of the body. They act as cofactors…
Q: For the determination of fatty acid composition, transesterification is done in a warm aqueous…
A: Transesterification refers to the reaction of esters with alcohol and carboxylic acids. These are…
Q: 8. In patients with diabctes mellitus type 1, the biochemical disorders result from changes in fucl…
A: Since you have asked multiple questions, we will solve the first three subparts of the question for…
Q: 1. Determine the isoelectric pH (pI) of the amino acids (a) Met, M, (b) Glu, E and (c) Lys, K. Show…
A: Isoelectric point(pI) is the pH at which the net charge on the species (here amino acid ) is 0 i.e.…
Q: ɡive me example about the arranɡements of heptapeptide such as Arɡ, Phe, Val and etc.
A: Proteins are made up of unique sequence of amino acids. This unique sequence determines the primary…
Q: Use examples to clearly Illustrate the meaning of the following terms and expression: (a) The Newman…
A:
Q: Draw and define the following terms: Binding Site Catalytic Site Allosteric Site Conformational…
A: Enzymes are proteins that play a major role in speeding up a biochemical reaction. They are…
Q: Indicate whether each of the following disaccharides is a reducing (R) or nonreducing (NR) sugar by…
A: Carbohydrates are also called saccharides because their basic components are sugars. Carbohydrates…
Q: Step 7: Determine the appropriate calculation for the pl of lysine. For lysine, the pK, of the amine…
A: Amino acids are the simple units that build the polypeptide chain of the protein. There are 20 types…
Q: Given a tripeptide Cys-His-Lys, Cys: Pk1 = 1.5; Pk2 = 10.8; PkR = 8.5 His: Pk1 = 1.6; Pk2 = 9.0; PkR…
A: Hi. Thank you for the question, As per the honor code, we are allowed to answer three sub-parts at a…
Q: 8. Hypercholesterolemia is a frequent complication of diabetes mellitus in patients with prolonged…
A: Glycation is a post-translational alteration of lysine, arginine, and the N-terminus of proteins…
Q: Decide which N atom in each molecule is most basic, and draw the product formed when each compound…
A: Zolpidem: Used in treating insomnia, that is difficulty in falling asleep. It belongs to the…
Q: Proteins that are synthesized by living organisms adopt abiologically active conformation. Yet when…
A: Ans: Protein: The chain of amino acids which are joined together by peptide bond is referred to as…
Q: C. Choosing the Proper Buffer Solution 1. Choosing the Proper Buffer Solution In Protein…
A: The processes that occur in the body require specific and stable pH range. Buffers are solutions…
Q: Answer questions for the following monosaccharide: H, Н—с — он Но —с —н Н—с —он d. Draw the product…
A: The bromine water test is a sort of test that is utilized to recognize glucose and fructose on the…
Q: Suppose you had separated the A and B chains of insulin by disulfide reduction. What chromatographic…
A: Insulin is an endocrine hormone, which regulate the blood sugar levels. This hormone made up of two…
Q: VỊ Give the complete name of the ff. sugars and indicate whether it is reducing or non-reducing. OH…
A: Carbohydrates can be categorized as both reducing and non- reducing sugars. The major difference…
Q: 5. You need the following standard protein concentrations: 4mg/mL, 1mg/mL, 0.25mg/mL, and…
A: Proteins are nitrogenous organic macromolecules that are essential for the proper functioning of…
Q: 1. Examine the synthetic glycoprotein, Molecule A, shown below: Protein- OH OH OH OH OH ÓH OH…
A: The polymer given in the question consists of glycoprotein molecule with the different sugar…
Q: For the chemical reaction that results in the formation of a peptide bond between two amino acids,…
A: The peptide bond is formed when the two amino acids are joined together with the release of water…
Q: Arachidonic acids * A. Linoleic polyunsaturated omega-6 fatty acid is its starting material. B.…
A: Lipids are not polymers. The simplest form of lipid is fatty acids which are a long chain of…
Q: Protein: SHAYNERSE Predict the products of the following reactions with the protein given, if there…
A: Given protein SHAYNERSE is…
Q: 8. Fat-soluble vitamins. Name the compound shown below. Explain: a. Which compound is the precursor…
A: A body requires certain organic molecules in small quantities in its diet to maintain proper growth…
Q: 5. Maltase is an enzyme that catalyzes the hydrolysis of the disaccharide maltose. This process…
A: Enzymes are substances which acts as biocatalysts in living organisms which increases the efficiency…
Q: (a) A decapeptide has the following amino acid composition: Ala2 , Arg, Cys, Glu, Gly, Leu, Lys,…
A: Since you have asked multiple questions, we will solve the first question for you. If you want any…
Q: 7. During amino acid catabolism, how is amino group removed and excreted in the form of urea? Please…
A: During amino acid catabolism, the amino group removed and excreted in the form of urea. The…
Step by step
Solved in 2 steps
- 1. The amino acid sequence for the protein lysozyme is given below. Estimate the isoelectric point for lysozyme protein. The pK, values are provided in Table 3.1. KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNT DGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKK IVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL Here's the sequence in this form: LYS VAL PHE GLY ARG CYS GLU LEU ALA ALA ALA MET LYS ARG HIS GLY Table 3.1 Typical pk, values of ionizable groups in proteins Group Acid Typical pK, Base Terminal a-carboxyl 3.1 group Aspartic acid Glutamic acid 4.1 N. Histidine 6.0 -N + H Terminal a-amino group 8.0 Cysteine 8.3 Тутosine 10.9 + H Lysine 10.8 H H. + N-H Arginine 12.5 N-H N-H Note: Values of pk, depend on temperature, ionic strength, and the microenvironment of the ionizable group. in1.Ala-Phe-Lys-Val-Val-Glu From the above polypeptide, what amino acid/s go/goes inside the cell after the following treatment: Chemotrypsin, thermolysin, then finally pepsin. What protein is left undigested? Write the primary structure of the undigested protein? 2.K-V-F-W-P-L-A-Y a.Chemotrypsin treatment b.Trypsin treatment c.Pepsin treatment d.Thermolysin treatment 3.Total acid hydrolysis of a pentapeptide complemented by total alkalinehydrolysis yields an equimolar mixture of 5 amino acids listed alphabetically, ala-cys,lys,phe,ser. N-terminal analysis with phenylisothiocyanate (PITC) generate PTH-ser. Trypsin digestion produces a tripeptide where N-terminal residue is cys and a dipeptide with ser as its N- terminal.Chemotrypsin digestion of the above tripeptide yields ala plus another dipeptide. A.What is the amino acid sequence of the tripeptide B.What is the amino acid sequence of the dipeptide derived from trypsin digestion? C.What is the primary structure of the original…Given the Ramachandran Plot below, identify the protein components that could adopt the phi-psi angle combination indicated by the number 3. (IF YOU COPY UR ANSWER FROM ANOTHER WEBSITE I WILL DISLIKE)
- S1.What functional group (pictured below) is used in the formation of ATP, the backbone of DNA, and the plasma membrane? R. - HO- asluolom OgH 910m ansa obyd to inuoms adisi69 101 P- Hnedenoi HO 9tom anisinos H 19w 1639 eniv blut viend ou nontel:oceansied bol-ngtsl s19 1591 a. Amino b. Carbonyl c. Ester d. Phosphate e. Alcohol Sabios onime Tertio of bensemoo Insietib ti aolem tsrll blas onims ns to neg at to quang ly snodibod for ogh quotgg) (CH3)₂ - CH₂ -CH-COOH + CH₂-CH-COOH -H₂O NH₂ OH NH₂ 4. Write the equation for the digestion (hydrolysis) of Phe-Asp-Ala. €a. An oligopeptide ALVGALGATPTPQMWSHSWRGVSIKS was digested with trypsin.Which method would be most appropriate for separating the products: ion exchange or gel filtration chromatography? Explain.b. Suppose that the peptide was digested with cyanogen bromide. What would be the optimal separation technique? Explain
- . The following diagram shows the biosynthesis of B12 coenzymes, starting with the vitamin. DMB is dimethylbenzimidazole. (a) What one additional substrate or cofactor is required by enzyme B? (b) Genetic deficiency in animals of enzyme C would result in exces- sive urinary excretion of what compound?10. o . Briefly discuss Ramchandran plot. . What is quaternary structure of proteins? Mention the role of various bond in its structure with the help of an example give its biochemical function. What are liposomes? Discuss their role in medicine. . Differentiate between cerebroside and ganglioside and one disorder associated with each. R9. H. State if/how Aureliano's mutation changes the amino acid sequence and describe the effect that change has, if any, on the protein.
- Given the Ramachandran Plot below, identify the protein components that could adopt the phi-psi angle combination indicated by the number 3.9. A daily diet of a 55-ycar-old woman, consisted of a 500 g of carbohydrates, 100 g of animal fats and 150 g of proteins, at the background of low physical activity. What possible consequences for the lipid metabolism such lifestyle could trigger? For the answer: a) compare the daily food consumption of the patient with the norm for this age and level of physical activity; b) draw the scheme of TAG synthesis in the liver and continue with their following transport to the tissues; c) draw the scheme of metabolic pathways which are more active in adipocytes of this patient compared with an individual of the same age consuming balanced dict; d) name the biologically active molecules released by adipocytes of this patient.Denatured protein is in a low energy state. What sort of explanation can you use to rationalize that statement? Hint: consider Gibbs free energy.