Identify the manipulated, responding and controlled variables in the experiment described above. Strength of Stimulus Number of Muscle Fibre Stimulated Mass Lifted by Muscle Contraction
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- Muscle Contraction In an experiment, the strength of a neural stimulus and the resulting muscle contraction are compared. A single motor neuron that synapses with one muscle fibre is observed in this experiment. One end of the muscle fibre is attached to a mass. The following data were obtained from the experiment. Number of Trials Strength of Stimulus (mV) Mass Lifted by Muscle Contraction (g) 1 20 0 2 40 0 3 60 50 4 80 50 5 100 Not Tested 6 120 50 *note that the voltage applied is positive in order to raise potential from resting to threshold Identify the manipulated, responding and controlled variables in the experiment described above. Strength of Stimulus Number of Muscle Fibre Stimulated Mass Lifted by Muscle ContractionIn an experiment, the strength of a neural stimulus and the resulting muscle contraction are compared. A single motor neuron that synapses with one muscle fibre is observed in this experiment. One end of the muscle fibre is attached to a mass. The following data were obtained from the experiment. Number of Trials Strength of Stimulus (mV) Mass Lifted by Muscle Contraction (g) 1 20 0 2 40 0 3 60 50 4 80 50 5 100 Not Tested 6 120 50 Is the threshold potential for this muscle fibre exactly 50 mV. Do you agree or disagree? Explain.Determine the isoelectric point of myofibrillar proteins here in this experimental data
- First, explain how resting membrane potential is established in terms of ion concentration and electric charge. Next, explain the process of neural signal transmission from an alpha motor neuron to the muscle fiber. Do this by explaining how an AP is generated (ions and membrane proteins) at the neuron, how the signal is propagated, what happens at the axon terminal, what happens at the motor endplate, and explain all the molecular events that occur to cause muscle contraction.Reflect back on the Muscle Fatigue investigation we did earlier in this Activity. Choose one of your classmate’s interpretation to one of these questions: What happened to your energy & ability to pinch the clothespin as you progressed through each trial? Why? What might cause one to be able to get more squeezes, in other words, to have less fatigue? Explain in terms of biological concepts. Suggest how the amount of ATP produced cause your muscle cells to be less efficient. When did this change in the amount of ATP produced occur in this investigation? How could you tell? Your muscles would probably recover enough after 10 minutes to operate at the original efficiency. Explain why. Show how specific details from the steps of cellular respiration add details to answer this question.Can you modify this experiment so that the mass lifted by the muscle contraction continues to increase for every trial? If yes, explain how it should be modified. If no, explain why.
- * The figure below is called the It shows the amount of tension generated by a muscle and the force of contraction depends on how stretched or contracted it was before it was stimulated. * 100 80 (d) 60 (e) Normal /range 40 (a) 20 1.2 μm 1.6 μm 2.1 μm 2.2 um 2.6μm 3.6 μη Decreased length Increased length Optimal resting length Tension (percent of maximum)The sliding-filament model of skeletal-muscle contraction assumes a sliding or slipping of interdigitating filaments of actin and myosin. Electron micrographs show that during contraction the actin and my-osin filaments remain of constant length while the distance between Z lines shortens. Explain how this happens in terms of the molecular structure of the muscle filaments. What is the role of regulatory pro-teins (troponin and tropomyosin) in contraction?An investigator is studying the electrophysical properties of gastrointestinal smooth muscle cells using microelectrodes. He measures the resting membrane potential of a cell to be -70 mV. The equilibrium potentials of different ions involved in generating the membrane potential are shown. ENa Ek Eca EM² Ecr +65 mV -85 mV +120 mV +10 mV -85 mV Which of the following is the most important contributor to the difference between the resting membrane potential and the equilibrium potential of potassium?
- The motor unit firing patterns are measured in a human hand muscle using an electromyography (EMG) recording. Which one of the following statements is the best description of the EMG pattern observed as the individual voluntarily attempts to make a low-level force of contraction in the muscle and steadily increases the force of contraction? Low amplitude spikes visible on the EMG trace at low force. Larger amplitude spikes become visible with increasing force of contraction. Low frequency of small amplitude spikes on the EMG trace at low force. Spike frequency and amplitude increase with increasing force. A large single deflection in the trace as the individual contracts the muscle. The deflection gets larger with increasing force. Low frequency of spikes on the EMG trace at low force. The frequency of spikes becomes more frequent with increasing force.Vhat are the two types of muscle movement categories? Give an example for both. Describe Swammerdam's experiment and Galvani's experiment with frog legs. What did they tell us about muscle contraction? What is the sliding-filament model for muscle contraction? Describe the role of actin and myosin of sarcomeres in the model (be specific). Describe how an action potential triggers muscle contraction. Know the specific molecules involved. . Describe the structural and functional differences between smooth, cardiac and skeletal muscles. What are the three types of skeletal muscle fibers and how do they differ in structure and function? Next « Previous MacBook ProDescribe the movement of myosin along an actin filament. Outline the primary molecular steps and explain how this process is used by cells. How many actin monomers within an actin filament would a myosin molecule need to ratchet in order to contract a cell by approximately 1 um? How fast could a non-muscle cell make this contraction compared to a muscle cell if the relative rates of myosin walks on F-actin are 4.5 um/sec and 0.04 um/sec for myosin II and I respectively?