Hypermethylation is thought to contribute to cancer by a. inhibiting DNA replication. b. inhibiting the expression of tumor-suppressor genes. c. stimulating the translation of oncogenes. d. stimulating telomerase.
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Hypermethylation is thought to contribute to cancer by
a. inhibiting
b. inhibiting the expression of tumor-suppressor genes.
c. stimulating the translation of oncogenes.
d. stimulating telomerase.
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Solved in 2 steps
- Most forms of cancer involvea. the activation of a single oncogene.b. the inactivation of a single tumor-suppressor gene.c. the activation of multiple oncogenes.d. the activation of multiple oncogenes and the inactivation ofmultiple tumor-suppressor genes.Which of the following are mechanisms by which cancer drugs work (select all that apply)? A. Inhibit activity of oncogene B. Promote apoptosis C. Promote terminal differentiation of cells D. Inhibit drug transporters E. Promote DNA damage.Which of the following factors contributes to angiogenesis as a result of a tumor growth? Select all that apply: a. Increasing tumor's access to oxygen and nutrients b. Increasing tumor's ability for growth, invasion, and metastasis c. Increasing expression of proto-oncogenes for cancer cells d. Increasing expression of tumor-suppressor genes for cancer cells
- Our government has finite funds to devote to cancer research.Discuss which of the following areas of research you think shouldreceive the most funding.A. Identifying and characterizing oncogenes and tumorsuppressorgenesB. Identifying agents in our environment that cause cancerC. Identifying viruses that cause cancer D. Devising methods aimed at killing cancer cells in the bodyE. Informing the public of the risks involved in exposure tocarcinogensIn the long run, in which of these areas would you expect successfulresearch to be the most effective in decreasing human mortalitydue to cancer?Normal (nonmutant) tumor-suppressor genes often functiona. as negative regulators of cell division.b. in the maintenance of genome integrity.c. in the stimulation of cell division.d. as both a and b.Different gene therapy approaches have been studied for cancer gene therapy. These approaches include? (select all that applies) a.immunotherapy, b. anti-angiogenic gene therapy, c.inhibition of tumor invasion, d.induction of apoptosis
- Which of the following demonstrates the link between oncogenes and cancer? a.Oncogenes do not have mutations that increase the activity or number of molecules that stimulate mitosis. b.Oncogenes produce molecules that inhibit mitosis. c.They are genes that transform tumor cells into normal cells. d.The mutations in oncogenes increase the activity or number of molecules that stimulate mitosis, leading to irregular cell division.What is a primary function of tumor suppressor genes?a. stop all cells from dividingb. stop certain cells from dividingc. help oncogenes produce oncoproteinsd. allow the cell to skip certain phases of the cellcycleTissues and differentiation a)Explain what is meant by termination and differentiation ).b) Explain the difference between an oncogenic and a tumour suppressor gene and describe how they are involved in the onset of cancer
- Sometimes, malignant cells do not stay properly anchored in tissues because of the loss of function of: a. cell walls b. oncogenes c. plasma membrane adhesion proteins d. nuclear membranes e. tumor suppressor genesWhich of the following is typical of cancer cells? A. The parent cell of the tumor contains a single mutation in a single checkpoint gene. B. Malignant cells migrate. C. Cancer cells lose the ability to divide. D. Products of oncogenes inhibit mitosis E. Benign tumors invade normal tissue.Please discuss the difference between cancers caused by tumor viruses and cancers caused by oncogenes. Does the etiology of a cancer influence its manifestation?