Huntington’s Disease is a dominant lethal disease that manifests later in life after many people have had children. If you were the child of a parent who was diagnosed with Huntington's, would you want to be tested for the condition? Why or why not?
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Huntington’s Disease is a dominant lethal disease that manifests later in life after many people have had children. If you were the child of a parent who was diagnosed with Huntington's, would you want to be tested for the condition? Why or why not?
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- A woman who is eight (8) weeks pregnant requests a direct test for Huntington’s disease on her fetus. She tells her geneticist that she wants the test because she recently discovered that there is a family history of the disease in her husband’s family. One of his parents is affected so he is at 50% risk of developing the condition. She is adamant that she does not want to give birth to a baby who is at risk of developing Huntington’s and says that the test will help her to ensure that this is not the case. In counseling, she reveals that she has discussed this issue several times with her husband but he has always said he is not willing to take a test. He does not want to know his status and is extremely anxious about the possibility that he might develop the condition. The woman and her husband are currently separated but are seeing a relationship counselor and trying to work things out. Despite this, the woman says they tend to fight a lot. When it is explained to her in counseling…In neurofibromatosis the phenotype does not always correspond to the genotype, what is this effect called and why may we observe this?If you were an older adult and were suffering from a condition for which there was no cure and very few treatment options, would you want to know about the disease or would you want your doctor and family to keep this information from you? Explain your choice.
- The father of three sons and two daughters begins to show symptoms of Huntington's disease. What is the probability that Sam, the man’s second oldest son (II-2), will suffer from the disease if he lives a normal life span? Sam’s mother and her ancestors do not have the disease. Sam's father was adopted, so we do not know his biological family history for Huntington disease. Explore all possible outcomes for Sam and explain your reasoning. What about the risk to Sam's sisters? Would that be the same or not?The father of three sons and two daughters begins to show symptoms of Huntington disease. What is the probability that Sam, the man’s second oldest son (II-2), will suffer from the disease if he lives a normal life span? Sam’s mother and her ancestors do not have the disease. Sam's father was adopted, so we do not know his biological family history for Huntington disease. Explore all possible outcomes for Sam and explain your reasoning. What about the risk to Sam's sisters? Would that be the same or not?Hereditary hemochromatosis is an autosomal recessive genetic disorder that causes the body to absorb too much iron from the diet. This excess iron is stored in the body's tissues and organs, particularly the skin, heart, liver, pancreas, and joints. Because humans cannot increase the excretion of iron, excess iron can overload and eventually damage tissues and organs. Anthony and Melinda met at a support group for individuals who have hereditary hemochromatosis. They were advised by their genetic counselor that it would be risky to have children, since both of them are homozygous for the same recessive allele that causes this condition. Nevertheless, they decided to have a child together. During Melinda’s pregnancy, amniocentesis and genetic testing were performed, and it was confirmed the fetus was homozygous for the hereditary hemochromatosis allele. At birth, the baby appeared completely normal, and as the child continued to grow and mature, the couple were surprised that he seemed…
- Sickle Cell Anemia Sickle cell anemia is a prevalent disease, which usually is seen in the African American community. It is an inherited disease where both parents have a copy of the gene and pass it along to offspring. Instructions Write a short essay about sickle cell anemia. Research our Virtual Library, the internet, and any other resource. Answer the following questions: What are the top current treatments for both adults and children? Among males and females affected, who tends to have more crises and why? Would stem cell therapy work? Why or why not? Name three celebrities who are affected by this disease.What would be the phenotypes for each of the following genotypes for Huntington’s Disease? a. Hh = b. hh =Suppose a couple brought to you their 8-year old boy with progressive muscle weakness, and difficulty in motor skills resulting to awkward manner of walking and running . The boy’s 15-year old sister and 11-year old brother appear to be unaffected. They have a normal father and a normal pregnant mother. The mother had a brother who died at 26 yrs. of age with similar findings that seemed to worsen with age. The mother also has a sister with the same findings but it only manifested during her 28th Her sister, who married an unaffected man, has two affected sons and a normal daughter. You suspect a diagnosis of Duchenne Muscular Dystrophy (DMD). Draw the pedigree of this family. Follow protocols in making a pedigree. Provide the genotype of all individuals in the pedigree. Please provide also the gene notation. What is the risk (probability) that the fetus is affected? Amniocentesis has to be performed in order to determine the sex of the fetus. What is the risk that the child will be…
- Sharon and Jack's son is diagnosed with G6PD deficiency. If the parents have never had signs or symptoms of the disease, how did their son inherit G6PD deficiency? If they have a female child, what are the chances she will have the deficiency as well?If your father were diagnosed with an inherited disease that develops around the age of 50, would you want to be tested to find out whether you would develop this disease? If so, when would you want to be tested? As a teenager or sometime in your 40s? If not, would you have children?If a test were available that could tell you whether you were likely to develop a disorder such as schizophrenia later in life, would you take the test? Why or why not? Rachel asked to see a genetic counselor because she was concerned about developing schizophrenia. Her mother and maternal grandmother both had schizophrenia and were institutionalized for most of their adult lives. Rachels three maternal aunts are all in their 60s and have not shown any signs of this disease. Rachels father is alive and healthy, and his family history does not suggest any behavioral or genetic conditions. The genetic counselor discussed the multifactorial nature of schizophrenia and explained that many candidate genes have been identified that may be mutated in individuals with the condition. However, a genetic test is not available for presymptomatic testing. The counselor explained that based on Rachels family history and her relatedness to individuals who have schizophrenia, her risk of developing it is approximately 13%. If an altered gene is in the family and her mother carries the gene, Rachel has a 50% chance of inheriting it.