Histone deacetylase (HDAC) enzymes a.Promote initiation of translation. b.Complex with hyperphosphorylated pRb. c.Repress E2F family activity. d.Add acetyl groups to E2F promoters. e.Promote initiation of transcription.

Histone deacetylase (HDAC) enzymes a.Promote initiation of translation. b.Complex with hyperphosphorylated pRb. c.Repress E2F family activity. d.Add acetyl groups to E2F promoters. e.Promote initiation of transcription.

Name: Histone deacetylase (HDAC) enzymes a.Promote initiation of translation
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Description: Histone deacetylase (HDAC) enzymes a.Promote initiation of translation.b.Complex with hyperphosphorylated pRb.c.Repress E2F family activity.d.Add acetyl groups to E2F promoters.e.Promote initiation of transcription.

Biology (MindTap Course List)

11th Edition

ISBN:9781337392938

Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Chapter14: Gene Regulation

Section: Chapter Questions

Problem 8TYU: Through alternative splicing, eukaryotes (a) reinforce gene inactivation (b) prevent transcription...

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Define the following terms: a. promoter b. consensus sequence c. operon d. chromatin-remodeling complex e. general transcription factors
Arrange the statements in their proper order by writing the corresponding letter (e.g. A) for each statement in the space provided below. A. The single-stranded RNA would complement the target RNA. B. Gene expression is inactivated once the mRNA is no longer accessible for translation. C. The risk-induced silencing complex which is composed of RNA and protein subunits is formed. D. Double-stranded, non-coding RNA is cleaved by Dicer. E. The mRNA can be cleaved or remain bound by the RISC. 1. 2. 3. 4. 5.
After treating cells in tissue culture with an HDAC inhibitor, which of the following is the most likely outcome? A. Repression of transcription B. Promoter methylation C. Enhanced splicing D. Activation of transcription E. Depends on the cell type
A principle function of 5' and 3' end modifications of eukaryotic mRNA is: a. to ensure that all nucleotides are phosphorylated b. to protect RNA from nucleolytic degradation c. to guide the removal of introns d. to serve as binding sites for translation release factors
Which of the following best explains how the prokaryotic expression of a metabolic protein can be regulated when the protein is already present at a high concentration? a.Repressor proteins can be activated and bind to regulatory sequences to block transcription. b.Regulatory proteins can be inactivated to increase gene expression. c.Transcription factors can bind to regulatory sequences to increase RNA polymerase binding. d.Histone modification can prevent transcription of the gene.
A scientist mutates eIF-2 to eliminate its GTP hydrolysis capability. How would this mutated form of eIF-2 alter translation? a. Initiation factors would not be able to bind to mRNA. b. The large ribosomal subunit would not be able to interact with mRNA transcripts. c. tRNAi-Met would not scan mRNA transcripts for the start codon. d. eIF-2 would not be able to interact with the small ribosomal subunit.
Which of the following is NOT TRUE about Eukaryotic Transcription: A. Occurs in the cytoplasm B. Pol II has 12 subunits C. Pol III transcribes tRNA genes D. It’s controlled by Cis-acting sequences E. Leads to specialization of cell function
Mutation of which of these sequences would have an effect on translational initiation? A. 3’ UTR B. Polyadenylation signal C. 5’ UTR D. upstream enhancer E. TATA box
Imagine that mutations occurred in one of the inverted repeat sequences within the rho-independent terminator sequence of a bacterium. What would likely be the consequence of this mutation? Select one: a. Transcription may not be initiated at all. b. Transcription may end prematurely. c. Transcription may be delayed. d. The rho protein won't be able to bind and transcription may not be terminate. e. Transcription may not be terminated and result in much longer RNA.
Define and describe the roles of the following in transcription: a. transcription factors b. RNA polymerase c. promoter d. sigma factor e. enhancer f. TATA box
For each statement about gene expression mechanisms, choose the correct end to the sentence. For each gene, the template strand for transcription is determined by…. The direction of translation is determined by…… The tissue-specificity of protein production is determined by…. choices: a. location of the start codon b. location of the promoter c. direction of polymerization by RNA polymerase d. none of these e. direction of movement of ribosomes f. overall orientation of the chromosome
Transcription of eukaryotic genes requires the presence of a promoter and usually the presence of enhancers. An enhancer: A. is a consensus sequence in DNA located where RNA polymerase first binds. B. may be located in various places in different genes. C. may be on either strand of DNA in the region of the gene. D. functions by binding RNA polymerase. E. stimulates transcription in both prokaryotes and eukaryotes.