ge You have found a plant-derived compound that interferes with microtubule assembly by binding to and blocking free cytosolic tubulin. This compound might help treat by interfering with the Select one: a. Cancer, p53 b. Cancer, cyclin c. Parkinsons, mitotic spindle d. Cancer, mitotic spindle e. Parkinsons, cyclin Next page
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- To design a drug that inhibits metastasis, which of the following strategies is the WORST idea? to disrupt cadherin complexes to inhibit Rho family proteins to inhibit ARP complex O to block myosin-based contractile structureMany common medications function by interrupting the normal operation of certain signal transduction pathways. Which of the following describes a possible mechanism by which a certain medication may interrupt a signal transduction pathway? A A medication enters the target cell and triggers apoptosis by causing the release of di- gestive enzymes from cell lysosomes. B A medication interacts with the phospholipid bi-layer of the cell membrane and in- creases its permeability. с D A medication binds to membrane-bound glucose proteins and acts as an allosteric in- hibitor that prevents the intake of glucose by the cell. A medication diffuses through the membrane of a target cell and inhibits an enzyme that normally synthesizes a second messenger.Vinblastine is a standard chemotherapeutic drug used to treat cancer. Because it interferes with the assembly of microtubules, its effectiveness must be related to Select one: a. inhibition of DNA synthesis. O b. myosin denaturation and inhibition of cleavage furrow formation. c. suppression of cyclin production. Od. inhibition of regulatory protein phosphorylation. O e. disruption of mitotic spindle formation. Next page
- Which of the following changes to the microtubule binding protein, Tau, commonly occurs in Alzheimerâ s and other neurodegenerative diseases? A Tau is hypo-phosphorylated and does not bind to microtubules to destabilize them. B Tau levels are so low in the cell that they only bind to some microtubules. C Tau is hyper-phosphorylated and does not bind to microtubules to stabilize them. D Microtubules are hyper-phosphorylated and do not bind to Tau.You have found a plant-derived compound that interferes with microtubule assembly by binding to and blocking free cytosolic tubulin. This compound might help treat ____________ by interfering with the _____ Select one: a. Cancer, p53 b. Cancer, mitotic spindle c. Parkinsons, mitotic spindle d. Cancer, cyclin e. Parkinsons, cyclin Clear my choiceWRITE ABOUT A THEME: ORGANIZATION The properties oflife emerge at the biological level of the cell. The highly regulated process of apoptosis is not simply the destruction of acell; it is also an emergent property. Write a short essay (about100–150 words) that briefly explains the role of apoptosis inthe development and proper functioning of an animal, and describe how this form of programmed cell death is a process thatemerges from the orderly integration of signaling pathways.
- Stem cells are undifferentiated cells with potential to give rise to many types of specialized cells. Lütfen birini seçin: O a. False O b. TrueA cell picks up mutations that allow it to move past the G1 and G2 checkpoints even if its growth factor is not present, These mutations a tightly to other cells and the extracellular matrix. As a result, this cell would .. O die O form a benign tumor form a malignant tumor that metasticizes O form a mass of normal tissueDescribe three ways in which the response of a cell to asignal can be terminated.
- of my celle chose are wels smaller than normal. According to Model 1, what part(e) of the cell cycle is (ere) ou likely being affected? Some cancerus me 7. In Model 1, if the length of the arrow represents time, then for those cancerous cells, what hap pens to the time that is necessary for the cell cycle? What implication might this have for doctors who are treating cancer patients? Why? Living things must grow and develop. At times they suffer injuries or damage, or cells simply wear out. New cells must be formed for the organism to survive. What process must occur to make a new, properly- functioning cell? Model 1 - Mitosis as Part of the Cell Cycle Prophase Metaphase Anaphase Mitosis How do living things grow and repair themselves! Replicated chromosome (2 sister chromatids) 0000 * Centriole Spindle fibers Nuclear membrane Telophase 1. Refer to Model 1. List the four phases in the mitosis process. 2. Where is mitosis in the cell cycle? Before 3. What three phases of the cell cycle…ge A mutation in p21 that destroys its binding site will Select one: a. inhibit transcription of p21 b. inhibit sarcomere relaxation c. inhibit cell division d. e, promote cell division inhibit sarcomere contraction Next paOur government has finite funds to devote to cancer research.Discuss which of the following areas of research you think shouldreceive the most funding.A. Identifying and characterizing oncogenes and tumorsuppressorgenesB. Identifying agents in our environment that cause cancerC. Identifying viruses that cause cancer D. Devising methods aimed at killing cancer cells in the bodyE. Informing the public of the risks involved in exposure tocarcinogensIn the long run, in which of these areas would you expect successfulresearch to be the most effective in decreasing human mortalitydue to cancer?