GABA is a neurotransmitter that binds to ligand-gated chloride (Cl-) ion channels, causing Cl- to move into the post-synaptic cell. A transporte protein moves GABA back into the presynaptic cell to terminate the effect of the neurotransmitter. If a neurophysiologist applies a drug that blocks this transporter protein, what would you expect to happen to the frequency of action potentials in the post-synaptic cell relative to the case with no drug? O A. Increase in the frequency of action potentials O B. Decrease in the frequency of action potentials O C. No effect

GABA is a neurotransmitter that binds to ligand-gated chloride (Cl-) ion channels, causing Cl- to move into the post-synaptic cell. A transporte protein moves GABA back into the presynaptic cell to terminate the effect of the neurotransmitter. If a neurophysiologist applies a drug that blocks this transporter protein, what would you expect to happen to the frequency of action potentials in the post-synaptic cell relative to the case with no drug? O A. Increase in the frequency of action potentials O B. Decrease in the frequency of action potentials O C. No effect

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter4: Principles Of Neural And Hormonal Communication

Section: Chapter Questions

Problem 4TAHL: Assume presynaptic excitatory neuron A terminates on a postsynaptic cell near the axon hillock and...

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Assume presynaptic excitatory neuron A terminates on a postsynaptic cell near the axon hillock and presynaptic excitatory neuron B terminates on the same postsynaptic cell on a dendrite located on the side of the cell body opposite the axon hillock. Explain why rapid firing of presynaptic neuron A could bring the postsynaptic neuron to threshold through temporal summation, thus initiating an action potential, whereas firing of presynaptic neuron B at the same frequency and the same magnitude of EPSPs may not bring the postsynaptic neuron to threshold.
An undisclosed drug (Drug A) is a drug that can block voltage-gated K+ channels when being introduced into the bloodstream. Explain the effects of Drug A on the action potentials produced by a neuron. If Drug A could be applied selectively to a presynaptic neuron that releases an excitatory neurotransmitter, analyse how would it alter the synaptic effect of the neurotransmitter on the presynaptic cell. Remark: The word count limit (250 words only), no less than 100 words
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