For the amino acid alanine, the major species in solution at pH 7 is the zwitterionic form, which has a negatively charged carboxylic acid group and a positively charged amino group. There is a less common neutral form in which neither group is charged. The carboxylic acid group of alanine has a p?a of 3 The amino group of alanine has a p?a of 8 Estimate the ratio of the concentration of the neutral amino acid species to the zwitterionic species at pH 7.   __?__x10^?

Chemistry & Chemical Reactivity
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Author:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
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Chapter24: Biochemistry
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Problem 2PS: (a) Draw the Lewis structure for the amino acid phenylalanine, showing the amino group and the...
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For the amino acid alanine, the major species in solution at pH 7 is the zwitterionic form, which has a negatively charged carboxylic acid group and a positively charged amino group. There is a less common neutral form in which neither group is charged.

The carboxylic acid group of alanine has a p?a of 3 The amino group of alanine has a p?a of 8

Estimate the ratio of the concentration of the neutral amino acid species to the zwitterionic species at pH 7.

 

__?__x10^?

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Step 1

According to the given question,

pKa of carboxylic acid group of alanine is given by = 3  pKa of amino group of alanine is given by  = 8

 

Find - The ratio of the concentration of the neutral amino acid species to the zwitterionic species at pH 7

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