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Explain how the disruptions in the electron transport chain leads to the production of reactive oxygen species and ultimately to cancer
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Solved in 2 steps
- Describe the key components of the electron-transport chain and how they are arrangedOxygen is the final electron acceptor in the electron transport chain. However, in the absence of oxygen the Kreb's cycle does not work either. Why does the Kreb cycle not proceed without oxygen when oxygen plays no direct part in its sequence of biochemical reactions? Hint: think of oxidation and reduction of electron carriers.Models such as the one shown in the illustration below are often used to represent the electron transport chain. Explain why this model is well-suited to this concept. Explain why metabolic processes such as cellular respiration and photosynthesis require a multi-stage release of energy, rather than a one-step reaction
- DESCRIBE the steps involved in the ATP production in the electron transport system (Only ETS, not glycolysis or Krebs cycle).Energy is required to reverse the flow of the electron transport chain. Why would this be so?Explain how oxidative phosphorylation is linked to electron transport and how the two processes can be uncoupled.
- A poison that prevents the transfer of electrons from the last [Fe-S] cluster of Complex I to coenzyme Q is added to a suspension of actively respiring mitochondria. Which of the following will be observed? ATP production would be impaired due to the uncoupling of oxidative phosphorylation from electron transport. ATP production would be reduced due to inhibition of the CoQ subunit of ATP synthase. ATP production would be reduced due to a decrease in the number of protons pumped out of the mitochondrial matrix. ATP production would be halted completely due to the block in electron transport through the electron transport chain.For Krebs Cycle(Citric Acid Cycle) what are steps of cellular respiration for both aerobic (oxygen present) and anaerobic (without oxygen) respiration. what are the Inputs and Outputs: Clearly indicate the key substrates, intermediates, and products at each stage. Location: Show where this stage of cellular respiration occurs within the cell (e.g., cytoplasm, mitochondria). Energy Production: Highlight the ATP and NADH production at this stage. Oxygen: Show where oxygen is used in the process (e.g., ETC) and where carbon dioxide is produced. Electron Carriers: Indicate the role of electron carriers such as NAD+ and FAD in transferring eleDiagrams: Use diagrams or icons to represent the structures and molecules involved, such as the mitochondria, glucose, ATP, and oxygen. Key Information like important facts or formulas relevant to cellular respiration, like the chemical equations for each stage.Complete the following table about the total products of the various pathways of cellular respiration that result in the complete oxidation of one molecule of glucose (C6H12O6). Number of CO2 produced Net number of ATP produced Number of NADH produced Number of FADH2 produced Glycolysis Pyruvate Oxidation Citric Acid Cycle