Define the following terms: a. sdLDL b. oxLDL c. cytochrome P450 d. atheroma e. abetalipoproteinemia
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Define the following terms:
a. sdLDL
b. oxLDL
c. cytochrome P450
d. atheroma
e. abetalipoproteinemia
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Solved in 2 steps
- Define the following terms:a. cytochrome P450b. mixed-function oxidasec. flavin-containing monooxygenased. detoxicatione. detoxificationDefine the following terms: a. ketogenic amino acid b. glucogenic amino acid c. L-amino acid oxidase d. Krebs urea cycle e. CPSIThe enzyme useful in the treatment of leukemia is which of the following? a. alpha-chymotrypsin b. Asparaginase c. Streptokinase d. Hyaluronidase
- Define the following terms: a. HSL b. CGI-58 c. fatty acid-binding protein d. β-oxidation e. carnitineDefine the following terms: a. thiolytic cleavage b. ketogenesis c. ketone bodies d. α-oxidation e. ACCSelecting the Exception Misfolded proteins are involved in four of the five following diseases. Select the exception. a. scrapie b. meningitis c. mad cow disease d. bovine spongiform encephalitis e. Creutzfeldt-Jakob disease
- For each of the following examples, indicate whether the drug is acting on physical process, chemical process or enzymatic system (your answer should be only; Physical, Chemical or Enzymatic). A. A drug is used as an antidote in lead poisoning and acts by binding to lead particles in body (chelation therapy). B. A drug acts to reduce flatulence and acts by reducing the surface tension of intestinal gas bubbles in the GI tract (e.g. Simethicone). C. A drug competes with alpha-glucosidase in intestine to reduce glucose conversion from disaccharides (e.g. Acarbose).Anemia is characterized by low hemoglobin levels or a reduced number of red blood cells (both of which transport oxygen to cells). A common symptom of anemia is tiredness. Please do not copy answers from another website/source. a) Briefly explain what the consequences are of anemia on cellular energy production. b) Suggest at least one other cellular effect of anemia and a brief explanation of this effect.Some are unable to taste thiourea and PTC. DNA sequence results for these individuals show a normal predicted amino acid sequence for the TAS2R38 gene. Provide an explanation that can account for insensitivity to thiourea. (a) First assuming a mutation involving the TAS2R38 gene (b) Then assuming a mutation in a gene other than TAS2R38
- Now answer the following questions: 1. Is this patient experiencing a disorder affecting anaerobic or aerobic metabolism? a) disorder affecting anaerobic metabolism. b) disorder affecting aerobic metabolism. c) None of them d) Both 2. You decide to perform assays to check the activity of one or more metabolic enzymes in the red blood cells. Which enzyme(s) would you check? a) Amylase b) Enzymes of pentose phosphate pathways c) Transaminase enzymes d) hexokinase, phosphofructokinase, and pyruvate kinaseOn the right is a diagram of plasma concentration of three metabolites: glucose, B- hydroxybutyrate, and free fatty acid of an experimental animal over weeks of starvation. 4. (a) Label the lines with the names of the three metabolites. Yellow: Red: 10 20 30 40 Blue: Days of starvation (b) What factor in the plasma binds to and transports free fatty acid (c) Where was B-hydroxybutyrate produced? Why it is produced? What are the purposes of producing it (d) How B-hydroxybutyrate is used as fuel in extrahepatic cells? Write down the reactions, enzymes, and cofactors (No need to elaborate on the TCA cycle). (e) How many ATP molecules or equivalent are generated after complete oxidation of one molecule of B-hydroxybutyrate? Show your calculations. Hint: You need to consider ATP consumption for bypassed steps that may normally yield or consume AT Plasma concentration (mM)A 9 year old mentally retarded girl with a protuberant abdomen, short stature, coarse facial features and cloudy corneas. skeletal malformations include dysostosis Multiplex and Bullet shaped middle phalanx .what is the enzyme deficient in this patient? A)Iduronate sulfatase B) beta - Galactosidase C)alpha - L- Iduronidase D) beta - Glucuronidase