Chargaff observed that the amount of OA. A+G; T+ C OB. A; T OC. purines; pyrimidines O D.A+T; G + C O E. G; C was not equal to the amount of in all tested organisms.
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- Here’s the fractional binding data for 2 different proteins (1 and 2) binding to a Drug D. Which of the following statements is/are true? 1 of 5: Each Protein 1 must only bind 1 molecule of D. 2 of 5: Each Protein 2 must bind 2 or more molecules of D. 3 of 5: Protein 2 binds significantly more D than Protein 1. 4 of 5: Protein 1 and 2 have roughly similar binding affinities for D. 5 of 5: Protein 1 binds faster to D than protein 2 does at low concentrations of D.Which of the following statements is TRUE regarding drugs that are weak acids/bases? A. if the target is inside the cell membrane, then the shape ofB. the active is the one that is not ionizedC. all answers are correctD. The degree of ionization is determined by the pH of the environmentE. The degree of ionization is determined by the pKa value of the drugOne example is phenobarbital There are some drugs that are active even after being metabolized. An example of a drug in question is….A. mandelic acidB. paracetamolC. mefenamic acidD. prontosil rubrumE. oleum ricini Which of the following statements is a FALSE statement regarding receptors?A. Not all optical isomers in drugs have the same activityB. To exert a biologic effect, drug molecules do not always have to form complexes with receptorsC. all answers are correctD. drug molecules have biological specificationsE. Drugs have biological activity at low concentrationsPlease help Can wearing a mask, limiting public spaces capacity, and having travel restrictions be justified because of Covid-19? Just a question not a writing assignment.
- A Structure B was derived from structure A. What was the main reason for incorporating the two ester groups? To decrease the stability of the drug. Hobbyk B To enhance hydrogen bonding interactions with the binding site. To increase the polarity of the drug. To alter the conformation of the molecule.In 1965, Monod, Wyman and Changeux put forward the MWC model for cooperative binding of ligands to oligomeric proteins, which also produced the MWC equation above. Give a detailed discussion on this model under the following points: Hoe die MWC model koöperatiwiteit verklaar. / How the MWC model accounts for cooperative effects. Wat die effek van allosteriese reguleerders sal wees op die algehele bindingskurwe. / What the effect of allosteric regulators will be on the overall binding curve. Hoe K-reeks en V-reeks ensieme beïnvloed word deur reguleerders. / How K-series and Vseries enzymes are affected by modifiers.what people should know about the public health response to COVID-19.
- For numbers A to I, determine the type of solubility each drug has based on USP: Freelysoluble Soluble Sparinglysoluble Slightlysoluble A. 1ml of water is needed to dissolve 1 gram of procaine B. 32ml of water is needed to dissolve 2 grams of morphine C. 1liter of water is needed to dissolve 5 grams of D. 150ml of water is needed to dissolve 5 grams of codeine sulfate E. 1liter of water is needed to dissolve 1 gram of phenobarbital F. 120 ml of water is needed to dissolve 1 gramof G. 1gram of silver sulfadiazine dissolves in 2 ml of H. 10grams of phenobarbital sodium can dissolve in 10 ml of I. 1gram of morphine sulfate requires 16 ml of water to beHow many grams of sodium chloride is required to render 80ml of 2% solution of ascorbic acid isotonic with blood. using The sodium chloride equivalent of drug = 0.18 Select one: O a. All of the answer is wrong. Ob 0.256 gm O c. 0.576 gm Od 0.432 gmThe Graph below shows the binding curves of two proteins (A and B) for the same ligand (L). Use this Graph and determine the dissociation constant, K, for both proteins. Which protein (A or B) has a greater affinity for ligand L? Which of the two proteins would be more easily inhibited by an antagonist? 1.0 Y 0.5 2 A 4 6 B 8 [L] (μM) 10 12 14 16
- Define the following terms:a. alkylating agentb. base analoguec. nonalkylating agentd. intercalating agente. ethidium bromideClassify the symmetrical arrangement ofthe subunits (e.g., C2 , C3 , D 2 , helical, icosahedral). 1. Proteobacterial nitrite sensor (3PNS):2. Pseudomonad oligosaccharide receptor (7POR):3. Adenoviral structural protein (8ASP)Explain this quesiton in descrition format whether non-barbiturate drug classes are labeled at a lower or higher selection compared to barbiturates?