Characterizing - in early clinical development- drug metabolism and clearance across populations that may metabolize or clear the drug differently (e.g., older adults and participants with liver or kidney dysfunction) will help avoid later exclusions and, more generally, will allow dose adjustment to optimize effectiveness and safety across different populations. A) True B) False

Ebk:Nutrition & Diet Therapy
10th Edition
ISBN:9780357391747
Author:DEBRUYNE
Publisher:DEBRUYNE
Chapter15: Medications, Diet-drug Interactions, And Herbal Products
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Characterizing - in early clinical development- drug metabolism and clearance across populations that may metabolize or clear the drug differently (e.g., older adults and participants with liver or kidney dysfunction) will help avoid later exclusions and, more generally, will allow dose adjustment to optimize effectiveness and safety across different populations. A) True B) False
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