Biomolecular Signaling Hydrogen sulfide and nitrogen monoxide can act as signaling agents in living cells. NO is often bound in a molecule named 5-nitrosoglutathione (GSNO) and is released in a reaction with H,S, producing glutathione (GSH) and thionitrous acid (HSNO): GSNO(aq) + H2S(aq) → GSH(aq) + HSNO(aq) The rate of the reaction at 25°C was determined by following the rate of consumption of H2S: a. Calculate the average rate of the reaction between t = 0.0 s and t = 50.0 s. b. Estimate the instantaneous rate for the reaction at t = %3D %3! 25.0 s. Time (s) [H2S] (µM) 0.0 250 25.0 158 50.0 98 75.0 71

Biomolecular Signaling Hydrogen sulfide and nitrogen monoxide can act as signaling agents in living cells. NO is often bound in a molecule named 5-nitrosoglutathione (GSNO) and is released in a reaction with H,S, producing glutathione (GSH) and thionitrous acid (HSNO): GSNO(aq) + H2S(aq) → GSH(aq) + HSNO(aq) The rate of the reaction at 25°C was determined by following the rate of consumption of H2S: a. Calculate the average rate of the reaction between t = 0.0 s and t = 50.0 s. b. Estimate the instantaneous rate for the reaction at t = %3D %3! 25.0 s. Time (s) [H2S] (µM) 0.0 250 25.0 158 50.0 98 75.0 71

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter4: Acids And Bases

Section4.6: Molecular Structure And Acidity

Problem 1Q: Acid-Base Equilibria Many factors contribute to the acidity of organic compounds. Electronegativity,...

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