6. In humans, hemophilia is a recessive and sex-linked character. A man and a woman (grandparents), both normal with respect to blood clotting have: 1 a hemophilic son who has a daughter who is normal; - a daughter who has normal blood and who has one hemophilic and one normal son; and - another daughter with normal blood who has five sons, all normal. What are the probable genotypes of grandparents, children, and grandchildren?

6. In humans, hemophilia is a recessive and sex-linked character. A man and a woman (grandparents), both normal with respect to blood clotting have: 1 a hemophilic son who has a daughter who is normal; - a daughter who has normal blood and who has one hemophilic and one normal son; and - another daughter with normal blood who has five sons, all normal. What are the probable genotypes of grandparents, children, and grandchildren?

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Description: 6. In humans, hemophilia is a recessive and sex-linked character. A man and a woman (grandparents),both normal with respect to blood clotting have:1a hemophilic son who has a daughter who is normal;- a daughter who has normal blood and who has one h

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter12: Mendel, Genes, And Inheritance

Section: Chapter Questions

Problem 7TYK: In cats, the genotype AA produces tabby fur color; Aa is also a tabby, and aa is black. Another gene...

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A heterozygous individual has a _______ for a trait being studied. a. pair of identical alleles b. pair of nonidentical alleles c. haploid condition, in genetic terms
1. In humans, the allele for normal blood clotting, H, is dominant to the allele for hemophilia, h. This is a sex-linked trait found on the X chromosome. A woman with normal blood clotting has four children: a normal son, a hemophiliac son, and two normal daughters. The father has normal blood clotting. What is the genotype for each member of the family?
1. Hemophilia is due to a sex-linked gene. It is recessive and found on the X chromosome. A woman who is a carrier for hemophilia marries a normal man. What will be the possible phenotypes of their children? Use a punnet square. 2. A phenotypically normal man, who has a hemophiliac brother, marries a normal woman, who is not a carrier. What is the probability that any of their children will be hemophiliac? Use a punnet square. 3. Color-blindness is an X-linked, recessive trait. If a normal-sighted woman, whose father was color-blind, marries a colorblind man, what is the probability that they will have a son who is color-blind? Use a punnet square. 4. A man and woman, both of normal vision, have: 1) a color-blind son (#1) who has a daughter of normal vision 2) a daughter (#1) of normal vision who has one color-blind son and one normal vision son 3) another daughter (#2) of normal vision who has five sons, all with normal vision What are the probable genotypes of the…
6. The pedigree below traces the inheritance of a particular disorder. Circles are females, squares are males. Shaded symbols are affected with the disorder (NOTE: "half-shaded" symbols are NOT used here, for heterozygous individuals). What is the mode of inheritance of this disorder: is it dominant or recessive? Autosomal or X-linked? What is the genotype of the three numbered individuals? 1 2. 3.
2. Hemophilia is an X linked recessive trait. There is a woman who is a carrier for hemophilia and marries a man with hemophilia. a) Complete the Punnett Square (it is a google drawing so you will have to double click it to go to the drawing and type in and around the square. Hold the CONTROL (or Command) button and press the PERIOD button to write a superscript/exponent.) b) What are the possible genotypes of the children? c) Could any of their children have hemophilia? If so, would the child be male or female? Explain your reasoning.
6. Hemophilia causes severe bleeding from minor wounds. The blood is unable to clot properly because one of the factors necessary for clotting is missing. Hemophilia is an inherited sex-linked recessive disorder transmitted on the X chromosome by mothers to their sons. i) A woman inherited the gene for hemophilia from her mother and marries a man who iş normal and has no hemophilia. What is the possibility that her children can have hemophilia?
1. Hemophilia is a disease inherited as a X-linked recessive trait while pattern baldness is controlled by an autosomal gene that is dominant in males and recessive in females. A hemophilic man who is also homozygous for baldness has children with a woman who is not hemophilic but a carrier and heterozygous normal-haired. Show the parental genotypes, the Genotypic ratio (GR) of the offspring and their phenotypic ratio. Separate the total number of the male offspring from female offspring. For example, if there are 8 total number of offspring, count how many are females and how many are males. So if there are 4 females, then the denominator for the genotypic ratio and phenotypic ratio for female offspring is 4. You can convert it to percentage if you want. Answer the following: a. Among the female offspring, what is the probability of having hemophilic but normal haired child? b. Among the male offspring, what is the chance of having a child with normal blood clotting but bald?
6. Haemophilia is a relatively uncommon, sex-linked condition that is determined by a recessive allele on the X chromosome. It is a condition in humans in which the blood fails to clot normally. The following diagram shows a pedigree for haemophilia. Joe Sally Tom Tina 1 Jim Sheila 2 3 ? Mary Barry 4 5 6 7 Affected male Unaffected male Affected female Unaffected female a) Determine the possible genotypes for Jim, Sheila and their children (Sally, Tom and Mary). Use the symbols XH for the normal allele and Xh for the mutant allele and Y for the Y chromosome. Briefly state your logic in each case. b) Tom and Tina are expecting their first child and want to know the probability that the child had haemophilia i) if it is a boy or ii) if it is a girl. How would you advise them?
8. Consider the following phenotype for hemophilia, a recessive X-linked blood clotting disorder, in decendents of Queen Victoria. Victoria is thought to have been a carrier for the recessive hemophilia allele. What is the probability that Princess Irene is also a carrier? Albert Victoria (1819–1901) Edward Empress Victoria Leopold Princess O O L Duke of Alice Helena Beatrice II of Hesse Christian Albany Kaiser George Princess Frederick (Alexandra) Victoria Leopold Maurice Eugenie Alice Wilhelm II V Irene Alix Tsarina of Athlone Nikolas II (wife of Alfonso XIII)
4. Consider the characteristics and pedigree of a couple: Woman: has normal vision but mother is color blind has normal blood clotting but father is hemophiliac not bald but both parents are bald Man: father is colorblind but mother has normal vision both parents have normal blood but the brother is hemophiliac bald but both parents are not bald. a) Give the genotypes of the following: i. ii. man i. woman's mother and father iv. man's mother and father woman
8. Huntington’s disease is a degenerative disease of the nervous system that strikes in middle age. The allele that causes the disease (H) is dominant to the allele that results in the normal condition (h). Answer the following questions about the inheritance of this disease. A. What is the genotype of a man who is normal but whose father had Huntington’s disease? B. What is the genotype of a woman who has Huntington’s disease if both of her parents had Huntington’s disease? C. If a man who is heterozygous for Huntington’s disease marries a woman who is normal, what would you expect for the genotypes and phenotypes of their children? D. If a normal man marries a woman who is homozygous for Huntington’s disease, what do you expect for the genotypes and phenotypes of their children?
5. A female child, Della, has the autosomal dominant condition of polydactyly. Della's mother has the normal number of fingers and toes like her parents and brother (Della's maternal grandparents and uncle). Della's father has six fingers on each hand and so did two of his three sisters and his mother (Della's paternal aunt and grandmother). Della has a younger brother who has the normal number of fingers and toes. Give the genotype of each parent and each child. Della's Mother Della's Father Della Della's Brother 5. Draw a pedigree demonstrating polydactyly in the family above. 7