B-cells participate in Select one: immunity and produce innate, proteasome inhibitors Ob. innate, antibodies O c. innate, MHC1 receptors Od. acquired, proteasome inhibitors Oe. acquired, antibodies
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- Match the immunity concept with the best description. _____ anaphylactic shock a. recognizes antigen _____ immune memory b. insufficient immune response _____ immune deficiency c. general defense mechanism _____ autoimmunity d. immune response against ones own body _____ antigen receptor e. secondary response _____ inflammation f. acute allergic reactionActivated complement proteins ________. a. puncture cells b. promote inflammation c. attract macrophages d. all of the aboveAntibodies are ________. a. antigen receptors c. proteins b. made only by B cells d. all of the above
- Type II hypersensitivities are due toa. IgE reacting with mast cellsb. activation of cytotoxic T cellsc. IgG-allergen complexes that clog epithelial tissuesd. complement-induced lysis of cells in the presence of antibodiesExamine Type IV hypersensitivities by completing each sentence. 54 Туре IV МНС I tuberculin Compared to Type III hypersensitivities, reactions primarily involve -cell activity. T allografts Type IV dysfunction is known as secondary antigen exposure. hypersensitivity for symptoms arise 1 to several days following contact dermatitis delayed One example, infectious allergy, occurs during the reaction in persons sensitized by tuberculosis Lysosome infection. xenografts GVHD which occurs after exposure to antigens in The most common delayed allergic reaction, however, is plant resins, drugs, or personal articles, and involves the production of inflammatory cytokines that cause blistering. Autografts В -mediated reactions, while Finally, host rejection of grafted tissue can occur due to occurs when passenger cells in the grafted tissue attack host cells. MHC II PsoriasisSome Type-II immunopathology mediated autoimmune diseases have manifestations inmultiple different organs. Discuss how antibodies to one single antigen can cause damage inmultiple sites throughout the body. Things you might discuss include, but are not limited towhere the antigen could be expressed, how antibodies are made, how they bind antigen,where they circulate, the ratios of antigen to antibody, mechanisms of the immune systemthat result in cellular/tissue damage, or how immune system components can affect otherorgans. You might also comment on what makes one antigen an attractive target rather thananother. Please do NOT comment on all the things listed above, they are just to get youthinking. If you are having trouble getting started, it might help to think about a specificdisease which affects multiple organs.
- A piece of foreign protein, after digestion, that triggers an immune response is called..? (best answer). Cytokine. O MHC Molecule. O Epitope O Antibody. Antigen. « PreviousNeutrophis are not able to present antigens to CD4 T celis even though they are phagorytic because Oa thoy can only present antigens to natural killer celis. Ob. they work for the innate defenses Oc they lack MHC I complexes Od. they lack MCH II compiexes QUESTION 11 Which of the following is lymphocyte that worka innately to remove intracellular pathogens? Oa. Basophil cel O b. Monetyte OG Natural killer cell Od B Lymphocyte QUESTION 12 All are chemical defenses of innate nonspecific immunity except: Oa. blinking O b. antimicrobial pepetides OG lysuzyme Od plasma acute-phase proteinaWhich of the following is a TRUE statement regarding the effect of high doses of corticosteroids, such as dexamethasone, on the imnune system? O None of the statements apply Functions to inhibit IgG secretion from autoimmune B cells O Functions to specifically inhibit cyclooxygenase-2 (COX-2) to decrease pain and inflammation Functions to inhibit enzyme phospholipase A2, which causes lethal disruption of WBC function (WBC death) OFunctions to inhibit enzyme phospholipase A2, which decreases cyclooxygenase- 2 (COX-2) levels
- Which of the following apply to a secondary immune response? O A small number of antigen-specific lymphocytes O A large population of the infectious agent O None of the statements apply O A large, antigen-specific memory cell population Symptomatic illness of the patient O A lag time of 5-7 daysA helper T cell can bind only to another cellthat hasa. MHC-II proteins.b. an epitope.c. an antigen-binding site.d. a complement-binding site.e. a CD4 protein.Place each events number listed below on the correct part of the “stages ofillness” graph (picture attached) to demonstrate the relationship between your body’s immuneresponse and your symptoms. Event Numbers: 1. The B cell clones itself into many plasma cells that are producing tons ofantibodies specific to the antigen. Memory B cells form.2. Plasma cells stop producing antibodies and memory B cells remain, ready foranother exposure to the antigens3. Antibody titre begins to decline4. The helper T-cell docks with a B cell shows the antigen to the B cell5. The antigen is engulfed by a macrophage and is present to a helper T cell