Assume, in this context, that the methoxy group is sterically smaller than the methyl group, an assumption that is supported by the fact that methoxy groups induce less axial strain than methyl groups in cyclohexane conformations. H H CH₂ Most stable H₂C cond most stable ast stable H H B CH₂ OCH OCH₂ H₂C HH C een Хроно H₂C CH₂ D [Choose] [Choose] [Choose] HH DOCHS H₂C H₂C H H F OCH₂

Assume, in this context, that the methoxy group is sterically smaller than the methyl group, an assumption that is supported by the fact that methoxy groups induce less axial strain than methyl groups in cyclohexane conformations. H H CH₂ Most stable H₂C cond most stable ast stable H H B CH₂ OCH OCH₂ H₂C HH C een Хроно H₂C CH₂ D [Choose] [Choose] [Choose] HH DOCHS H₂C H₂C H H F OCH₂

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter2: Alkanes And Cycloalkanes

Section: Chapter Questions

Problem 2.46P

See similar textbooks

Similar questions

What is the energy difference between the axial and equatorial conformations of cyclohexanol (hydroxcycyclohexane) and how do you find it?
what is the most stable conformation of (1R, 2S, 5R)-1,2,5-trimethylcyclohexane
Consider 1-bromo-2-methylpropane and draw the following. (a) The staggered conformation(s) of lowest energy (b) The staggered conformation(s) of highest energy
Gibbs free energy differences between axial-substituted and equatorial-substituted chair conformations of cyclohexane were given in Table 2.4. (a) Calculate the ratio of equatorial to axial tert-butylcyclohexane at 25C. (b) Explain why the conformational equilibria for methyl, ethyl, and isopropyl substituents are comparable but the conformational equilibrium for tert-butylcyclohexane lies considerably farther toward the equatorial conformation.
cỌH CH2OH ОН Н На H ÓH In its most stable chair conformation, indicate the orientation of each of the labeled groups in this substituted cyclohexane. Group a: Group b: Group c:
Cyclohexane derivatives exist primarily in the most stable of the available chair conformations. Give the position, axial or equatorial, of each of the three groups shown when the ring is in the most stable chair conformation. If a group divides its time equally between axial and equatorial positions, indicate this with ax/eq.
Which of the following cyclohexane conformation is (are) consider to be the most stable conformation for cis-1,2-dimethylhexane? I II III
Sketch a potential energy diagram for rotation around a carbon–carbon bond in propane. Identify each potential energy maximum and minimum with a structural formula that shows the conformation of propane at that point. Does your diagram more closely resemble that of ethane or of butane? Would you expect the activation energy for bond rotation in propane to be more than or less than that of ethane? Of butane?
cỌH CH OH ОН Н Ha ОН In its most stable chair conformation, indicate the orientation of each of the labeled groups in this substituted cyclohexane. Group a: equatorial Group b: axial Group c: equatorial
Write structural formulas for all ketones with the molecular formula C6H12O and give each its IUPAC name. Which of these ketones are chiral?
Consider 1-bromopropane, CH3CH2CH2Br. (a) Which of these is the lowest energy conformation?
Which is the most stable conformation of the following alcohols? In general, how do I find the most stable conformation?