According to the paper, F486 is a phenylalanine residue (i.e., an amino acid that is part of a chain that forms a protein) on SARS-CoV-2. It has an important interaction with ACE2 (best seen in Fig. 1(C) and Fig. 2(A)). Looking at this phenylalanine and the green residues surrounding it, which statement best describes the interaction that could be occurring?a) It forms a hydrogen bond with Y83. b) It forms a dipole-dipole interaction with M82. c) It forms London dispersion forces with surrounding residues. d) It encounters repulsions from surrounding residues. 1. As you can see in Fig. 1(C), there is an interaction between A475 on SARS-CoV-2 and $19on ACE-2. A475 is the amino acid alanine, and S19 is serine. Remember, amino acidsform chains through a condensation reaction, as illustrated here:https://chem.libretexts.org/Bookshelves/Introductory Chemistry/Introductory Chemistry (CK-12)/25%3A Organic Chemistry/25.18%3A Condensation Reactions). Here arethose structures, from Wikipedia: "Copy/paste the link into your browser"AlanineSerineH3C.HO.HOOHNH2Skeletal formuls of L-Skeletal lormula of L-alarineserineBall-and-stick modelBal-and-stick modelSpace-filing modelSpace-fiing model

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Answered: According to the paper, F486 is a…

Introduction to General, Organic and Biochemistry

11th Edition

ISBN:9781285869759

Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Chapter22: Proteins

Section: Chapter Questions

Problem 22.99P

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According to the paper, F486 is a phenylalanine residue (i.e., an amino acid that is part
of a chain that forms a protein) on SARS-CoV-2. It has an important interaction with
ACE2 (best seen in Fig. 1(C) and Fig. 2(A)). Looking at this phenylalanine and the green
residues surrounding it, which statement best describes the interaction that could be
occurring?

a) It forms a hydrogen bond with Y83.

b) It forms a dipole-dipole interaction with M82.

c) It forms London dispersion forces with surrounding residues.

d) It encounters repulsions from surrounding residues.

1. As you can see in Fig. 1(C), there is an interaction between A475 on SARS-CoV-2 and $19
on ACE-2. A475 is the amino acid alanine, and S19 is serine. Remember, amino acids
form chains through a condensation reaction, as illustrated here:
https://chem.libretexts.org/Bookshelves/Introductory Chemistry/Introductory Chemist
ry (CK-12)/25%3A Organic Chemistry/25.18%3A Condensation Reactions). Here are
those structures, from Wikipedia: "Copy/paste the link into your browser"
Alanine
Serine
H3C.
HO.
HO
OH
NH2
Skeletal formuls of L-
Skeletal lormula of L-alarine
serine
Ball-and-stick model
Bal-and-stick model
Space-filing model
Space-fiing model

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