Answer A,B,C a) Describe the chemistry of the four main steps of B-oxidation of fatty acids (include the names of the enzymes).b) Describe the chemistry of the four main steps of fatty acid biosynthesis (include the names of the enzymes).c) In what other ways do these two opposing pathways differ?d) Draw the structures of the following found in B-oxidation (use abbreviations R- and COAS- to simplify drawing):Fatty Acyl-CoA, trans-A²-Enoyl-CoA, L-B-Hydroxyacyl-CoA, B-Ketoacyl-CoA and Acetyl-CoAe) Draw the structures of the following found in FA biosynthesis (use abbreviations –S–KSase -S-ACP to simplifydrawing):Acetyl-S-KSase, Malonyl–S-ACP, Acetoacetyl–S–ACP, D-B-Hydroxybutyryl–S-ACP, Crotonyl–S–ACPand Butyryl–S-ACP

Answered: a) Describe the chemistry of the four…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Answer A,B,C

a) Describe the chemistry of the four main steps of B-oxidation of fatty acids (include the names of the enzymes).
b) Describe the chemistry of the four main steps of fatty acid biosynthesis (include the names of the enzymes).
c) In what other ways do these two opposing pathways differ?
d) Draw the structures of the following found in B-oxidation (use abbreviations R- and COAS- to simplify drawing):
Fatty Acyl-CoA, trans-A²-Enoyl-CoA, L-B-Hydroxyacyl-CoA, B-Ketoacyl-CoA and Acetyl-CoA
e) Draw the structures of the following found in FA biosynthesis (use abbreviations –S–KSase -S-ACP to simplify
drawing):
Acetyl-S-KSase, Malonyl–S-ACP, Acetoacetyl–S–ACP, D-B-Hydroxybutyryl–S-ACP, Crotonyl–S–ACP
and Butyryl–S-ACP

Expert Solution

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Fats are esters of fatty acids that serve as an energy reservoir for the human body. The process by which fatty acids are cleaved to derive energy is known as the beta-oxidation of fatty acids. Fatty acids are broken down to acetyl CoA which are further broken down into chains of fatty acyl CoA. Mitochondria is the site where beta-oxidation takes place inside the cell. During the fatty acid synthesis, the acetyl CoA with the help of NADPH and other enzymes is converted to fatty acids. The cytoplasm is the particular site for this synthesis inside the cell.

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