A 62-year-old man is initially seen in the Emergency Room complaining of difficulty with speech and swallowing due to an enlarged tongue. Physical examination also reveals a large, sublingual hematoma. In addition, multiple ecchymoses of his skin are noted. He has no history of trauma nor has there been any pervious episodes of bleeding. Coagulation studies show: Platelet Count: 180,000/cumm PT: 12 sec APPT: 72 sec TCT or thrombin time: 10 sec Fibrinogen: 225% Additional laboratory studies reveal: (Mixing Studies) Normal plasma:  20%       50%         80% Patient plasma   80%       50%         20% Repeat APPT:     72 sec   70 sec      68 sec   Questions: What additional Laboratory test to confirm the diagnosis? Give the relevance of the laboratory tests ordered to the case. Why it is necessary?

Essentials of Pharmacology for Health Professions
7th Edition
ISBN:9781305441620
Author:WOODROW
Publisher:WOODROW
Chapter25: Cardiovascular Drugs
Section: Chapter Questions
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A 62-year-old man is initially seen in the Emergency Room complaining of difficulty with speech and swallowing due to an enlarged tongue. Physical examination also reveals a large, sublingual hematoma. In addition, multiple ecchymoses of his skin are noted. He has no history of trauma nor has there been any pervious episodes of bleeding. Coagulation studies show:

Platelet Count: 180,000/cumm

PT: 12 sec

APPT: 72 sec

TCT or thrombin time: 10 sec

Fibrinogen: 225%

Additional laboratory studies reveal: (Mixing Studies)

Normal plasma:  20%       50%         80%

Patient plasma   80%       50%         20%

Repeat APPT:     72 sec   70 sec      68 sec

 

Questions:

  1. What additional Laboratory test to confirm the diagnosis?
  2. Give the relevance of the laboratory tests ordered to the case. Why it is necessary?
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