50-year-old postmenopausal woman has emphysema. This lung disease impairs the ability to oxygenate the blood, so patients experience significant fatigue and shortness of breath. To alleviate these symptoms, oxygen is typically prescribed, and this patient has a portable oxygen tank she carries with her at all times,

Microbiology for Surgical Technologists (MindTap Course List)
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Author:Margaret Rodriguez, Paul Price
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Chapter22: Emerging, Recurring, And Reappearing Diseases
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A 50-year-old postmenopausal woman has emphysema. This lung disease impairs the ability to oxygenate the blood, so patients experience significant fatigue and shortness of breath. To alleviate these symptoms, oxygen is typically prescribed, and this patient has a portable oxygen tank she carries with her at all times, breathing through nasal cannulae. Before she began using oxygen, her red blood cell (RBC) count was 6.3 x 1012/L. After oxygen therapy for several months, her RBC count dropped to 4.0 x 1012/L.

 

  1. What physiologic response explains the elevation of the first RBC count?
  2. What hormone is responsible? How is its production stimulated? What is the major way in which it acts?
  3. What explains the decline in RBC count with oxygen therapy for this patient?
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