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3. Drug resistance in bacteria can only be inherited genetically.
OPTIONS: True False
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- 2. Define the term "Pharmacodynamics" and explain how this concept helps in the understanding of the role and efficacy of anti-retroviral drugs. Definition:5. complication management in management of chemotherapy?3. The most factor that increase the immunogenicity is Formulation Glycosylation Sequence variation Route of application
- 4. You seed a 10cm tissue culture plate with a 4x10^6 HeLa cells. HeLa fells have a doubling time of 24h. At 9am on Tuesday you wish to infect the cells with poliovirus at an MOI of 10. Your poliovirus stock is at a concentration of 4x10^7 pfu/ml. What volume of your poliovirus stock do you need to add to your plate of cells?2. Select any ONE of the following experimental procedures and describe how it is done and what the experiment is used Rescue protocol b. Temperature sensitive mutants Genetic mosaics a. M с. ill d. Positional cloning rse Clonal analysis е. f. Fate mappingActivity 5 Critically study the diagram below and then carry out the activity that follows: 1. Cells harvested from patient In lab, virus altered so cannot reproduce 7. -Altered cells produce desired protein A gene is inserted into the virus 6. Altered cells injected into patient's body 4. Altered virus mixed with patient's cells 5. Cells become genetically altered 1. Follow all the steps in the diagram and then draw it in your observation notebook. 2. List out some of the notable disorders treated by using gene therapy. 3. Predict the future of gene therapy.
- 12. Breaking the Chain of Transmission of Infection Messaging about how to contain Covid-19 and reduce the spread of SARS-CoV-2 has changed dramatically since the first appearance of the disease in January of this year. Misinformation is rampant and the general public is often confused about the best way to proceed. Using your knowledge as a biologist, write an essay that explains to your friends and family how disease is spread and how each step promoted by the Centers for Disease Control helps to break the chain of transmission and flatten the curve. Include how each of the following techniques a) breaks the chain of transmission of disease, especially COVID-19; and b) the consequences to an individual and to society at large of failing to implement the technique. Wash your hands often, for at least 20 seconds. Don’t touch your face. Clean and disinfect surfaces. Wear a face covering in public Stay at least 6 feet from others. Stay at home.16. Why 70% alcohol is used as a disinfectant? Circle all possible explanation. O A. Alcohol denatures proteins in the plasma membrane or viral body thus destroying it rendering them ineffective and causing cell death or inhibiting reproduction. V B. Water is used as a catalyst for the denaturation of proteins that leads to cell membrane destruction. O c. Alcohol can be taken in orally, destroys cells that entered the body. V D. Diluted alcohol evaporates slower compared to a pure alcohol since its highly volatile, providing more time for chemical reactions to take place. O E. 100% alcohol coagulates proteins instantly creating a film that protects the other proteins from further coagulation preventing other alcohol molecules to react and destroy the cell membrane. O F. Alcohol has a dehydrating effect and may interfere with the functioning of cell membranes.4. Which of the following antibiotics contains beta-lactam ring? A. Penicillin B. Fluoroquinolones C. Erythromycin D. Co-trimoxazole E. Tetracycline
- 5. Define bacterial resistance to antibiotics. Why is bacterial resistance a concern in the clinical settings?1.) An orphan disease may be a rare disease (according to US criteria, a disease that affects fewer than 200,000 people. Often, researchers do not get funding for orphan diseases. This includes pharmaceutical industry for drug treatment. Discuss how funding should be spent on orphan diseases.Topic: Resistance to antibiotics 11. Once resistance occurs, what has the scientific community had to do? 12. Do antibiotics only affect negative bacteria? explain. 13. What are the most feared diseases due to antibiotic resistance? 14. Should antibiotics be used against viruses? explain. 15. How can we avoid antibiotic resistance?