2-Ethyl-1-hexanol was needed for the synthesis of the sunscreen octyl p-methylcinnamate. Show how this alcohol could be synthesized (a) by an aldol condensation of butanal and (b) by a malonic ester synthesis starting with diethyl malonate.

Q: The intramolecular aldol reaction of 6-oxoheptanal [CH3CO(CH2)4CHO] can yield three cyclic…

A:

Q: Show how the p-nitro-N-methylaniline can be synthesized from benzene:

A: In first step, bromination occurs in benzene to give bromobenzene. Then, in bromobenzene, nitration…

Q: When phenylacetaldehyde (C6H5CH2CHO) is dissolved in D2O with added DCl, the hydrogen atoms α to the…

A:

Q: Show how the p-nitroaniline can be synthesized from benzene:

A: Synthesis of p-nitroaniline from benzene using various processes is described below.

Q: show how to synthesize each compound from an organohalogen compound and an oxirane, followed by a…

A: Organohalogen compounds are those hydrocarbons whose one or more hydrogen atoms got substituted by…

Q: Propose a synthesis of the anti-inflammatory drug Fenclorac from phenylcyclohexane.

A: Fenclorac is an anti-inflammatory drug that is used during mild to severe inflammation. The…

Q: Propose a mechanism for the acid-catalyzed hydration of methylidenecyclohexane to give…

A:

Q: 3,5-Dibromo-4-hydroxybenzenesulfonic acid is used as a disinfectant. Propose a synthesis of this…

A: Phenol is reacted to concentrated sulfuric acid to give 4-hydroxybenzenesulfonic acid and…

Q: The following questions pertain to the esters shown and behavior under conditions of the Claisen…

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Q: From what aldehyde or ketone could each of the following be prepared by reduction with NaBH4 or…

A:

Q: The compound 3,5,5-trimethyl-2-cyclohexenone can be synthesized using acetone and ethyl acetoacetate…

A: Michael reaction: The reaction occurs with a variety of α,β-unsaturated carbonyl compounds such as…

Q: Show how the m-bromobenzonitrile can be synthesized from benzene:

A: Benzene is an aromatic compound. It consists of a six membered cyclic ring having alternate double…

Q: Propose a detailed mechanism for the following reactions:  a) Reaction of 3-methylbutanal and…

A: Mechanism of Claisen ester condensation reaction:

Q: Give the structure of compounds A to E in the following reaction sequence.

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Q: Provide a detailed, stepwise mechanism for the acid-catalyzed formation of acetophenone dipropyl…

A: When ketone reacts with alcohol first it form hemiketal and then this hemiketal further react with…

Q: What is the product resulted due to the reaction of 2-hydroxy-3-methoxybenzaldehyde with ethyl…

A: We have to give the products of the given reactions under basic condition.

Q: Propose a mechanism for the bromination of ethoxybenzene to give o- and p-bromoethoxybenzene

A:

Q: Show how the following ketones might be synthesized from the indicated acids, usingany necessary…

A: Friedal crafts acylation is an electrophlic aromatic substitution reaction. In this reaction, the…

Q: 2-Phenylindole is prepared from the reaction of acetophenone and phenylhydrazine, a method known as…

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Q: Show how the o-nitrophenol can be synthesized from benzene:

A:

Q: Show how the following ketones might be synthesized from the indicated acids, usingany necessary…

A: This is the reaction given

Q: Show how you would synthesize the following compounds, starting with benzene or toluene and any…

A: The formation of 1-bromo-4-methylbenzene from toluene is shown below.

Q: Propose a synthesis for 3,5-dichloro-2-methoxybenzoic acid starting from phenol.

A: Synthesis for 3,5-dichloro-2-methoxybenzoic acid  from phenol is given as

Q: What product will be obtained from 2,3-Diphenylbutane-2,3-diol on heating it in an acidic medium…

A: Structure of 2,3‐Diphenylbutane -2,3-diol is   Which has (-OH) functional groups.

Q: A molecule of propanone reacts with an cyclohexylethanone in presence of aq. NaOH to combine…

A: In First  reaction  First  step is aldol reaction  then removal  of water its called  aldol…

Q: Upon hydration of 2-heptyne in the presence of HgSO4 and H2SO4, the two carbons of the triple bond…

A: Regioselective reaction are those reaction where nucleophile attack at site in preference to another…

Q: Suggest starting materials for the formation of the following aldol products: (a) (b) O I `H H

A: Aldol condensation: The alpha hydrogen of carbonyl compounds is acidic in nature and it is removed…

Q: Show how to synthesize alkynes by eliminations from alkyl halides and by the additions and substitu-…

A: The reaction is a nucleophilic substitution reaction in which acetylides are involved. Acetylide is…

Q: single reaction sequence: a certain ketone undergoes alkylation to give new ketone, when reacted…

A: Acetone reacts with t-BuOK gives enolate ion. This enolate ion reacts with propyl bromide gives…

Q: Show how alkylation and acylation of enamines and lithium enolates are usedsynthetically. Give…

A: SOLUTION: Step 1: Enamines are used as intermediates to form carbon-carbon bonds in reactions.…

Q: The following compound undergoes Benzilic Acid Rearrangementto yield a hydroxyacid salt. Propose a…

A: A question based on Benzylic acid rearrangement, which is to be accomplished.

Q: Show how you would synthesize the following compounds, starting with benzene or toluene and any…

A: SOLUTION: Step 1: Toluene on nitration gives para-nitro toluene. Para-nitro toluene on further…

Q: The Favorskiireaction involves treatment of an a-bromo ketone with base to yield a ring-contracted…

A:

Q: Phenyl 4-aminosalicylate is a drug used in the treatment of tuberculosis. Propose a synthetic route…

A: There are number of functional group associated with organic compounds which impart specific…

Q: 2-Phenylindole is prepared from the reaction of acetophenone and phenylhydrazine, a method known as…

A:

Q: 2. Propose a mechanism for the following transformation and explain why this type of reaction is…

A:

Q: Enamines normally react with methyl iodide to give two products: one arising from alkylation at…

A: The reaction is given below:

Q: For each compound, show the products obtained from ozonolysis, followed by treatment with dimethyl…

A: Since you have posted question with multiple sub-parts, we are entitled to answer the first three.

Q: Show how enols, enamines, and enolate ions act as nucleophiles. Give mechanismsfor acid-catalyzed…

A: Given nucleophiles,               Enols, enamines, and enolate ions.

Q: Provide the structure of the two organic product(s) which results when 2-bromo-2-methylbutane is…

A: 2-bromo-2-methylbutane on reacting with sodium ethoxide to form two organic products.  Reaction of…

Q: Show how you would synthesize the following compounds, starting with benzene or toluene and any…

A: The synthesis of 4-butylphenol from benzene has to be shown.

Q: Show how the p-bromoanisole can be synthesized from benzene:

A: The chlorination of benzene gives chlorobenzene, which is further reacted with sodium hydroxide to…

Q: 2. Intramolecular aldol cyclization of 3,3-dimethyl-2,5-nonanedione with aqueous NaOH yields a…

A:

Q: To obtain 2,4,4-trimethyl-2-pentanal, write down the reaction mechanism using 2,2-dimethylpropanal…

A: IMPORTANT POINTS: The product can be formed by cross aldol condensation.   In this reaction two…

Q: Propose a mechanism for the acid-catalyzed reaction of cyclohexanone with ethylene glycol to give…

A: A mechanism for the acid-catalyzed reaction of cyclohexanone with ethylene glycol to give…

Diol

In chemistry there are so many chemical compounds that have a hydroxyl group but a chemical compound having two hydroxyl groups (-OH) is termed as a diol. It also implies the presence of two alcohols whereas polyols contain two or more than two hydroxyl groups (-OH). Glycol or 1,2-diol is an aliphatic diol that has two alcohol groups on adjacent carbon atoms. In industries, the most commonly used diol is ethylene glycol.