10.52 A food-frequency questionnaire is used to measure dietary intake. The respondent specifies the number of servings of various food items he or she consumed over the previous week. The dietary cholesterol is then quantified for each respondent. The researchers were inter- ested in assessing if there was an association between dietary cholesterol intake and high blood pressure. In a large sample of individuals who had completed the questionnaire, 250 persons with a high dietary cholesterol intake (greater than 300 mg/day) were selected, and 250 persons with a low dietary cholesterol intake (less than 300 mg/day) were selected. The 500 selected participants had their medical histories taken and were classified as having normal or high blood pressure. The data are given here. Dietary Cholesterol High Low Total Blood Pressure High 159 78 237 Low 91 172 263 Total 250 250 500 a. Compute the difference in the estimated risks of having high blood pressure (#₁ - #₂) for the two groups (low versus high dietary cholesterol intake). b. Compute the estimated relative risks of having high blood pressure groups (low versus high dietary cholesterol intake). for the two c. Compute the estimated odds ratio of having high blood pressure for the two groups (low versus high dietary cholesterol intake). d. Based on your results from parts (a) (c), how do the two groups compare?
10.52 A food-frequency questionnaire is used to measure dietary intake. The respondent specifies the number of servings of various food items he or she consumed over the previous week. The dietary cholesterol is then quantified for each respondent. The researchers were inter- ested in assessing if there was an association between dietary cholesterol intake and high blood pressure. In a large sample of individuals who had completed the questionnaire, 250 persons with a high dietary cholesterol intake (greater than 300 mg/day) were selected, and 250 persons with a low dietary cholesterol intake (less than 300 mg/day) were selected. The 500 selected participants had their medical histories taken and were classified as having normal or high blood pressure. The data are given here. Dietary Cholesterol High Low Total Blood Pressure High 159 78 237 Low 91 172 263 Total 250 250 500 a. Compute the difference in the estimated risks of having high blood pressure (#₁ - #₂) for the two groups (low versus high dietary cholesterol intake). b. Compute the estimated relative risks of having high blood pressure groups (low versus high dietary cholesterol intake). for the two c. Compute the estimated odds ratio of having high blood pressure for the two groups (low versus high dietary cholesterol intake). d. Based on your results from parts (a) (c), how do the two groups compare?
Chapter16: Adult And Pediatric Dosages Based On Body Surface Area
Section: Chapter Questions
Problem 12SST
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Transcribed Image Text:10.52 A food-frequency questionnaire is used to measure dietary intake. The respondent
specifies the number of servings of various food items he or she consumed over the previous
week. The dietary cholesterol is then quantified for each respondent. The researchers were inter-
ested in assessing if there was an association between dietary cholesterol intake and high blood
pressure. In a large sample of individuals who had completed the questionnaire, 250 persons with
a high dietary cholesterol intake (greater than 300 mg/day) were selected, and 250 persons with a
low dietary cholesterol intake (less than 300 mg/day) were selected. The 500 selected participants
had their medical histories taken and were classified as having normal or high blood pressure.
The data are given here.
Dietary Cholesterol
High
Low
Total
1
Blood Pressure
High
159
78
237
Low
91
172
263
Total
250
250
500
a. Compute the difference in the estimated risks of having high blood pressure (, - #₂)
for the two groups (low versus high dietary cholesterol intake).
b. Compute the estimated relative risks of having high blood pressure
groups (low versus high dietary cholesterol intake).
for the two
c. Compute the estimated odds ratio of having high blood pressure for the two groups
(low versus high dietary cholesterol intake).
d. Based on your results from parts (a)-(c), how do the two groups compare?
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