1. NaOHOH2PhH2. AcidPh+PhOH 2The Cannizarro reaction is a base-catalyzed disproportionation ofaldehydes that have no \alpha -hydrogen (e.g., R = phenyl). Write amechanism for this reaction showing all electron pushing. Derive a kineticexpression for your mechanism and predict the kinetic order in aldehyde andhydroxide. What experiments would you perform to test the validity of yourmechanism?

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Answered: 1. NaOH 2 Ph H 2. Acid Ph OH + Ph OH

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1. NaOH 2 Ph H 2. Acid Ph OH + Ph OH

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter22: Reactions Of Benzene And Its Derivatives

Section: Chapter Questions

Problem 22.14P

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Question

2The Cannizarro reaction is a base-catalyzed disproportionation of
aldehydes that have no \alpha -hydrogen (e.g., R = phenyl). Write a
mechanism for this reaction showing all electron pushing. Derive a kinetic
expression for your mechanism and predict the kinetic order in aldehyde and
hydroxide. What experiments would you perform to test the validity of your
mechanism?

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