QUESTION 21You are studying two proteins that you suspect cap the ends of actin filaments. To detemine if they do and to determine which end they cap, you measure filament formation as a function of actin concentration in the absence of either protein, in the presence of protein 1 and in the presenceof protein 2 (each individually). You get the results below. Which protein caps the plus end and which caps the minus end?(A) NO ADDED PROTEIN(B) PROTEIN 1(C) PROTEIN 2filamentmonomerfilamentmonomerfilamentmonomer0.20.40.60.80.20.40.60.80.20.40.60.8actin (uM)actin (µM)actin (µM)O Neither protein caps either end of actin.O Both proteins cap the plus endO Protein 1 caps the minus end and protein 2 the plus end.O Protein 2 caps the minus end and protein 1 the plus end

Ans Protein 1 caps the minus end of the filament as it has lowered the critical concentration of…

Answered: STION 21 e studying two proteins that…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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QUESTION 11 What is the molecular explanation for the observation that the I band appears to shorten in a muscle sarcomere that is undergoing contraction? A The actin filaments shorten. B The sarcomere is disassembled. C a and b D The myosin filaments walk along the actin filaments towards the Z-line to increase the amount of overlap between actin and myosin. E The myosin filaments shorten.
QUESTION 14 Which of the following statements is FALSE? A Microtubules will rapidly disassemble in response to a drop in the ATP concentration. B G-actin monomers and alpha-tubulin/beta-tubulin dimers assemble into filaments in their ATP-bound and GTP-bound forms, respectively. C Microtubules are stabilized by microtubule-binding proteins, such as Tau. D Actin-binding proteins allow F-actin to assemble in cells in many different ways. E Hydrolysis of ATP and GTP changes the conformation of the monomers once they are incorporated into actin filaments and microtubules, respectively.
QUESTION 13 What is the mechanism by which microtubules can rapidly shrink, or undergo â catastrophe?â A At low levels of ATP, tubulin subunits are not added to the + end of the microtubule. B At low levels of GTP, beta-tubulin subunits at the + end of the microtubule hydrolyze GTP, undergo a conformational change, and destabilize the filament so that the filament starts to disassemble from the + end. C At low levels of GTP, tau proteins are phosphorylated and bind to the microtubule to destabilize the + end. D At high levels of GTP, tubulin subunits are more quickly added to the â end than to the + end of the microtubule, resulting in a shrinking + end of the microtubule. E At low levels of ATP, the microtubules rapidly disassemble since ADP-bound tubulin subunits are lost at both the + and â ends of the filament.
Question 33 What occurs when the sarcomere length of skeletal muscle is reduced beyond the length w optimum force is developed? The amount of calcium released by the sarcoplasmic reticulum is reduced as length increases. The thin filaments are pulled away from one another, thereby reducing their ability to interact with The thick filaments are pulled away from one another, thereby reducing their ability to interact with The thick filaments overlap one another, thereby reducing their ability to interact with actin. The thin filaments overlap one another with myosin bumping into the Z-line, thereby causing the fo generated by cross bridges to be exerted on the sarcomere itself rather than transmitted to the end muscle fiber. Previous Question 34 During exercise, CO2 produced by muscle cells causes hyperemia. This is an example of Vasodilation; active Vasodilation; reactive Vasoconstriction : active Vasoconstriction: reactive
QUESTION 10 Which of the following is NOT true of intermediate filaments? A They provide mechanical strength to cells. B They are composed of 8 oppositely oriented tetramers that are assembled into a rope-like filament. C They have a non-polar orientation. D They are rigid and do not deform before breaking E Keratins, neurofilaments, vimentin, and desmin are examples of intermediate filaments.
QUESTION 10 Which of the following statements is false concerning the motor protein families of kinesins and dyneins? Kinesins and dyneins A OG OD. have tails that bind to the actin filaments move along microtubules, actin filaments, and intermediate filaments derive their energy strictly from GTP hydrolysis All of the above
Question 7. What is the rate-limiting step in the formation of an actin microfilament?
Question 41 The sliding filament model of contraction involves----- A) Actin and myosin sliding past each other and partially overlapping B) The Z discs sliding over the myofilaments C) Actin in myosin lengthening in order to slide past each other D) The shortening of thick filaments so that the thin filaments slide past Please provide a brief explaination of each one correct or incorrect. THANK YOU!!
Question 17 What is the nucleotide sequence of the DNA strand that is complementary to 5-АTCGCAACTGTCAСТА-3 A 5-UAGUGACAGUUGCGAU-3' B 5'-TAGCGTTGACAGTGATA-3" с) 5-АТCАСTGTCААCGCTA-3 D 5'-TAGTGACAGTTGCGAT-3'
Question 17 What is the nucleotide sequence of the DNA strand that is complementary to 5'-ATCGCAACTGTCACTA-3 A 5'-UAGUGACAGUUGCGAU-3' B 5-TAGCGTTGACAGTGATA-3 5'-ATCACTGTCAACGCTA-3 D 5'-TAGTGACAGTTGCGAT-3'
QUESTION 12 What is most likely to occur in a cell when the levels of free GTP-bound tubulin subunits are very high in the cytoplasm? A The GTP cap on the end of the microtubules will shrink. B Microtubules will lengthen by adding tubulin subunits to their + ends. C The GTP-bound tubulin subunits will move into the nucleus. D Microtubules will undergo catastrophe and shorten. E Microtubules will lengthen by adding tubulin subunits to their - ends.
QUESTION 15 Which of the following molecules is NOT a component of desmosomes? A Intermediate filaments B Actin C Plakoglobin D Desmoplakin E Desmocolin

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STION 21 e studying two proteins that you suspect cap the ends of actin filaments. To detemmine if