Label the diagram of the immune response with the events that occur at each site during a type I hypersensitivity reaction. Secondary lymphoid organ B (e.g. lymph node) Allergen Lymphatic A flow IN D C Lymphatic flow OUT Answer Bank Answer Bank PAMPs on allergens are recognized by APCs, inducing phagocytosis. IgE is secreted into local tissue. Smooth muscle contraction, increased mucus production, and vasodilation occur. Immune cells release the polarizing cytokine IL-4. TH2 cells induce B-cell class switching to IgE. FCERI signaling activates mast cells, basophils, and eosinophils. Allergens bind IgE antibodies that are bound to the surfaces of granulocytes. Histamine, heparin, and proteases are released into the local tissue. Phagocyte Phagocyte containing allergen Cytokines Sensitized mast cell Histamine, heparin, proteases TH cell B cell Secreted antibody
Label the diagram of the immune response with the events that occur at each site during a type I hypersensitivity reaction. Secondary lymphoid organ B (e.g. lymph node) Allergen Lymphatic A flow IN D C Lymphatic flow OUT Answer Bank Answer Bank PAMPs on allergens are recognized by APCs, inducing phagocytosis. IgE is secreted into local tissue. Smooth muscle contraction, increased mucus production, and vasodilation occur. Immune cells release the polarizing cytokine IL-4. TH2 cells induce B-cell class switching to IgE. FCERI signaling activates mast cells, basophils, and eosinophils. Allergens bind IgE antibodies that are bound to the surfaces of granulocytes. Histamine, heparin, and proteases are released into the local tissue. Phagocyte Phagocyte containing allergen Cytokines Sensitized mast cell Histamine, heparin, proteases TH cell B cell Secreted antibody
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter12: Body Defenses
Section: Chapter Questions
Problem 1SQE
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Question
Chapter 15- Allergy, hypersensitives, and chronic inlfammation: Kuby Immunology Textbook
Transcribed Image Text:Label the diagram of the immune response with the events that occur at each site during a type I
hypersensitivity reaction.
Secondary
lymphoid organ
B (e.g. lymph node)
Allergen
Lymphatic
A
flow IN
D
C
Lymphatic
flow OUT
Answer Bank
Answer Bank
PAMPs on allergens are recognized by APCs, inducing phagocytosis.
IgE is secreted into local tissue.
Smooth muscle contraction, increased mucus production, and vasodilation occur.
Immune cells release the polarizing cytokine IL-4.
TH2 cells induce B-cell class switching to IgE.
FCERI signaling activates mast cells, basophils, and eosinophils.
Allergens bind IgE antibodies that are bound to the surfaces of granulocytes.
Histamine, heparin, and proteases are released into the local tissue.
Phagocyte
Phagocyte
containing allergen
Cytokines
Sensitized mast cell
Histamine, heparin,
proteases
TH cell
B cell
Secreted antibody
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