Drug G is available as a weak acid (WA) and has two salt forms. Their properties are listed below: Log Ko/w Aqueous solubility Very slightly soluble Slightly soluble Sparingly soluble Drug G forms MW WA 416 Da 3.3 Sodium Salt 460 Da | 2.8 Potassium Salt 520 Da 1.9 Drug G is available in the following formulations: Oral Solution Oral Suspension Immediate release tablet Based on the information provided, answer the following questions: 20. Which form of the drug is present in the Oral solution dosage form and why? 21. Which dosage form has the fastest onset of action? 22. Which dosage form has the smallest particle size? 23. Which dosage form will have the highest patient compliance?

Drug G is available as a weak acid (WA) and has two salt forms. Their properties are listed below: Log Ko/w Aqueous solubility Very slightly soluble Slightly soluble Sparingly soluble Drug G forms MW WA 416 Da 3.3 Sodium Salt 460 Da | 2.8 Potassium Salt 520 Da 1.9 Drug G is available in the following formulations: Oral Solution Oral Suspension Immediate release tablet Based on the information provided, answer the following questions: 20. Which form of the drug is present in the Oral solution dosage form and why? 21. Which dosage form has the fastest onset of action? 22. Which dosage form has the smallest particle size? 23. Which dosage form will have the highest patient compliance?

Chemistry: The Molecular Science

5th Edition

ISBN:9781285199047

Author:John W. Moore, Conrad L. Stanitski

Publisher:John W. Moore, Conrad L. Stanitski

Chapter13: The Chemistry Of Solutes And Solutions

Section: Chapter Questions

Problem 107QRT

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