Answer the following questions related to the separation of a mixture containing the following molecules: Compound 1 Structure OH 2 3 4 OH OH (a) What is the DOMINANT intermolecular force that will attract each compound to bind to silica gel? Compound 1 Intermolecular Force 2 3 4 H-Bonding H-Bonding Dipole-Dipole H-Bonding (b) The following compounds were separated by silica gel chromatography. Each compound was collected and placed in flasks labeled A, B, C and D respectively, in order of their elution from the column (i.e., the compound in flask A eluted first, B eluted second, C eluted third, and D eluted last). Indicate which compound 1-4 you would expect in each flask. Flask A Compound 3 B 2 C 1 D 4

Answer the following questions related to the separation of a mixture containing the following molecules: Compound 1 Structure OH 2 3 4 OH OH (a) What is the DOMINANT intermolecular force that will attract each compound to bind to silica gel? Compound 1 Intermolecular Force 2 3 4 H-Bonding H-Bonding Dipole-Dipole H-Bonding (b) The following compounds were separated by silica gel chromatography. Each compound was collected and placed in flasks labeled A, B, C and D respectively, in order of their elution from the column (i.e., the compound in flask A eluted first, B eluted second, C eluted third, and D eluted last). Indicate which compound 1-4 you would expect in each flask. Flask A Compound 3 B 2 C 1 D 4

Principles of Instrumental Analysis

7th Edition

ISBN:9781305577213

Author:Douglas A. Skoog, F. James Holler, Stanley R. Crouch

Publisher:Douglas A. Skoog, F. James Holler, Stanley R. Crouch

Chapter28: High-performance Liquid Chromatography

Section: Chapter Questions

Problem 28.7QAP

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