20 Carbamazepine tablets were found to weigh 10.000 g in total. The tablets were ground to a fine powder using a pestle and mortar. A 313.2 mg sample of the powder was boiled with 25ml ethanol for a few minutes. The hot mixture was stirred in a closed flask for 10 minutes and filtered through sintered glass. The flask and filter were washed with ethanol and the washings combined with the filtrate. The cooled mixture was made up to 100ml with ethanol (soln A). 5ml of the ethanol extract was diluted to 250ml with ethanol (soln B) and the absorbance of the resulting solution was found to be 0.598 absorbance units at a wavelength of 285nm. The A1%,1cm was 490? a) Calculate the total amount (in mg) of carbamazepine in solution B (1 decimal) Answer = mg b) Calculate the total amount (in mg) of carbamazepine in solution A (1 decimal) Answer = mg C) Calculate the amount (in mg) of carbamazepine in a single tablet. (1 decimal) Answer =

20 Carbamazepine tablets were found to weigh 10.000 g in total. The tablets were ground to a fine powder using a pestle and mortar. A 313.2 mg sample of the powder was boiled with 25ml ethanol for a few minutes. The hot mixture was stirred in a closed flask for 10 minutes and filtered through sintered glass. The flask and filter were washed with ethanol and the washings combined with the filtrate. The cooled mixture was made up to 100ml with ethanol (soln A). 5ml of the ethanol extract was diluted to 250ml with ethanol (soln B) and the absorbance of the resulting solution was found to be 0.598 absorbance units at a wavelength of 285nm. The A1%,1cm was 490? a) Calculate the total amount (in mg) of carbamazepine in solution B (1 decimal) Answer = mg b) Calculate the total amount (in mg) of carbamazepine in solution A (1 decimal) Answer = mg C) Calculate the amount (in mg) of carbamazepine in a single tablet. (1 decimal) Answer =

Appl Of Ms Excel In Analytical Chemistry

2nd Edition

ISBN:9781285686691

Author:Crouch

Publisher:Crouch

Chapter14: Chromatography

Section: Chapter Questions

Problem 9P

See similar textbooks

Similar questions

Human saliva contains the enzyme α-amylase which hydrolyzes polysaccharide acetal linkages. A soda cracker (containing starch) was carefully ground; the crumbs were distributed evenly between two test tubes. The first test tube contained only water, while the second contained a 1% solution of α-amylase. Both mixtures were heated to 35°C for 10 minutes and filtered. The filtrates were tested with iodine solution and Benedict’s solution. Use the following results to answer the questions below. Mixture Iodine test Benedict’s Test cracker in water dark blue blue cracker in water and α-amylase red red-orange precipitate a. Was the starch from the cracker/water mixture hydrolyzed? Was the starch from the cracker in the 1% α-amylase solution hydrolyzed? b. Which cracker contained reducing sugars?
250 mL of water sample was collected from a river and sent to a laboratory to determine the concentration of the total suspended solid. In the laboratory, 5 mL of the water sample was transferred to a 100 mL volumetric flask before diluted with distilled water to 100 mL. After that, 50 mL of the diluted water sample was transferred to a funnel containing a glass fiber filter and attached to a glass flask with the sidearm connected to a operating vacuum pump. Transferred diluted water sample was left drained through the glass filter before glass fiber was transferred to an oven to heat at 105 oC under a constant weight of 0.2654 g was obtained. If the initial weight of the glass fiber filter is 0.2431 g. Calculate the amount of the suspended solid in mg unit contained in the 250 mL collected water sample.
A sample of a soil was analysed for K+ as follows. A 2.50 g sample of soil was dissolved in acid and diluted to volume in 100 mL volumetric flask. A 10 mL of the resulting solution was transferred by pipet to a 50 mL volumetric flask and diluted to volume. An analysis showed that the concentration of K+ in the final solution was 9.81 ppm. What was the weight percent of K+ in the original soil?
A 15.00 g sample containing mixed alkali and other inert components was dissolved and diluted to 300 mL with water. A 20 ml, aliquot was titrated with 5.02 mL of 0.5352 M HCI to reach PHP endpoint. Another 20 mL aliquot was titrated to the BCG endpoint, using up 18.87 mL of titrant in the process. Identify the alkali components and their percent weight.
A sample of an infusion was diluted 10 ml to 250 ml and then 10 ml to 200 ml. It was thenanalysed and was found to contain sodium at 0.789 mg/100 ml. Calculate the concentrationof sodium in the original sample in %w/v. The sample was composed of a mixture of sodiumlactate and sodium carbonate in equimolar amounts. Calculate the amount of sodiumlactate and sodium carbonate in mg/10 ml of the sample (Na = 23, lactate = 89, carbonate =60)
Oral rehydration salts are stated to contain the following components: Sodium Chloride 3.5g Potassium Chloride 1.5g Sodium Citrate 2.9g Anhydrous Glucose 20.0g 8.342 g of oral rehydration salts are dissolved in 500 ml of water. 5 ml of the solution is diluted to 100 ml and then 5 ml is taken from the diluted sample and is diluted to 100 ml. The sodium content of the sample is then determined by flame photometry. The sodium salts used to prepare the mixture were: Trisodium citrate hydrate (C6H5Na3O7, 2H2O) MW 294.1 and sodium chloride (NaCl) NW 58.5. Atomic weight of Na = 23. The content of Na in the diluted sample was determined to be 0.3210 mg/100 ml. Determine the % of stated content of Na in the sample. The stated should be 104.5, how??
Oral rehydration salts are stated to contain the following components: Sodium Chloride 3.5g Potassium Chloride 1.5g Sodium Citrate 2.9g Anhydrous Glucose 20.0g 8.342 g of oral rehydration salts are dissolved in 500 ml of water. 5 ml of the solution is diluted to 100 ml and then 5 ml is taken from the diluted sample and is diluted to 100 ml. The sodium content of the sample is then determined by flame photometry. The sodium salts used to prepare the mixture were: Trisodium citrate hydrate (C6H5Na3O7, 2H2O) MW 294.1 and sodium chloride (NaCl) NW 58.5. Atomic weight of Na = 23. The content of Na in the diluted sample was determined to be 0.3210 mg/100 ml. Determine the % of stated content of Na in the sample.
A 500.0 μL aliquot of a ferric chloride solution is added to a 50.00 mL volumetric flask. To this flask is added 10 mL of 2M sodium acetate, 2 mL of 10 wt% NH4OCI, 3 mL of 5 wt% 1,10-phenanthroline, and enough DI water to fill the remaining volume of the flask for a total volume of 50.00 mL. Based on the UV-Visible light absorbance, the concentration of [Fe2+]=2.6 ppm. What is the concentration of Fe3+ ion in the original ferric chloride solution? O 3.85 X 103 ppm O 260.0 ppm O 260 ppm O 130 ppm
You are analyzing the effluent from a lotion plant for parabens using HPLC. You have a working standard solution with a concentration of 59.4 ppm which returned a Peak Height of 10,164 and Peak Area of 5,315. You take 44.4 L of the water sample and concentrate it to 0.3 L and analyze this solution. The Peak Height is 9,119 and the Peak Area is 6,320. What is the concentration of parabens in the effluent of the plant in mg/L to two decimal places.
A 25.00mL wastewater sample was analyzed for its Mg2+ content using a standard gravimetric method. the sample was diluted to 3.00L and an 11.00mL aliquot was treated to precipitate magnesium as MgNH4PO4.6H2O using (NH4)2HPO4 as the precipitating agent. the precipitate was then filtered, washed, dried, and ignited resulting in a 0.1325mg Mg2P2O7 residue. How much Mg (in ppm) is present in the original sample
A solution composed of 50% ethanol (EtOH), 10% methanol (MeOH), and 40% water (H20) is fed at the rate of 100 kg/hr into a separator that produces one stream at the rate of 60 kg/hr with the composition of 80% ELOH, 15% MEOH, and 5% H20, and a second stream of unknown composition. Calculate the composition (in %) of the three compounds in the unknown stream and its flowrate in kg/hr. F = 100 kg/hr mass fr 0.50 >P = 60 kg/hr mass fr Separator 0.80 МеОН 0.15 0.05 1.00 ELOH ELOH MEOH 0.10 0.40 1.00 W = ? kg/hr H,0 kg/hr mass fr ELOH mEtOH WEIOH MEOH mMeOH OMEOH H,0 mH,0 WH2O W 1.00
In the laboratory, a student was tasked to prepare a stock solution of HCl for titration. The available analytical grade HCl solution in the stock room was labelled 35% w/v HCl. The student proceeded to prepare the stock solution by mixing 10mL of the HCl solution with 490mL of analytical grade water. Then, the solution was further diluted by adding 5mL, since the total volume of the solution did not reach the 500mL etched mark on the volumetric flask. To prepare the titrant, the student mixed 10mL of the stock solution, then added 40mL of analytical grade water. The titrant was subsequently used to determine the concentration of two titrand. *Use the table as a reference 1. What is the normality of the available HCl reagent in the stock room?* 5.08 N 10.15 N 20.3 N 11.0 N None of the choices 2. What is the normality of the stock solution of HCl?* 0.09N 0.10N 0.11N 0.12N None of the choices 3. What is the normality of the titrant?*…